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The composite hydrogel exhibits adhesive property that is superior to clinically used fibrin and cyanoacrylate glues. The gelation time of the composite hydrogel could be regulated via changing the amounts of Bioglass which endows the hydrogel with good injectability. The in vivo experiment confirms that this composite hydrogel has good bioactivity to stimulate angiogenesis and enhance chronic wound healing. Moreover, for the first time, the concentrations of the bioactive ions released from the composite hydrogel in situ are quantified during wound healing using a microdialysis technique, and a correlation of the in vitro and in vivo concentration of ions released from the hydrogel is determined, which is extremely important for understanding the bioactivity mechanisms of Bioglass\/bioceramic\u2010based biomaterials and designing biomaterials for tissue regeneration.<\/jats:p>","DOI":"10.1002\/adhm.201800144","type":"journal-article","created":{"date-parts":[[2018,5,30]],"date-time":"2018-05-30T02:41:12Z","timestamp":1527648072000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":104,"title":["Bioglass Activated Albumin Hydrogels for Wound Healing"],"prefix":"10.1002","volume":"7","author":[{"given":"Yanling","family":"Zhou","sequence":"first","affiliation":[{"name":"State Key Laboratory of High Performance Ceramics and Superfine 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