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While there are simply not enough donor organs available for transplantation, there is a need to seek other therapeutic avenues as current dialysis modalities are insufficient. The field of regenerative medicine and whole organ engineering is emerging, and researchers are looking for innovative ways to create (part of) a functional new organ. To biofabricate a kidney or its functional units, it is necessary to understand and learn from physiology to be able to mimic the specific tissue properties. Herein is provided an overview of the knowledge on tubular and vascular basement membranes' biochemical components and biophysical properties, and the major differences between the two basement membranes are highlighted. Furthermore, an overview of current trends in membrane technology for developing renal replacement therapies and to stimulate kidney regeneration is provided.<\/jats:p>","DOI":"10.1002\/adhm.201800529","type":"journal-article","created":{"date-parts":[[2018,8,9]],"date-time":"2018-08-09T10:03:58Z","timestamp":1533809038000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Renal Tubular\u2010 and Vascular Basement Membranes and their Mimicry in Engineering Vascularized Kidney Tubules"],"prefix":"10.1002","volume":"7","author":[{"given":"Anne Metje","family":"van Genderen","sequence":"first","affiliation":[{"name":"Division of Pharmacology Utrecht Institute for Pharmaceutical Sciences  3584 CG Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitske","family":"Jansen","sequence":"additional","affiliation":[{"name":"Division of Pharmacology Utrecht Institute for Pharmaceutical Sciences  3584 CG Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Cheng","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Center Utrecht University Medical Center Utrecht  3584 CT Utrecht The Netherlands"},{"name":"Department of Nephrology and Hypertension University Medical Center Utrecht  3508 GA Utrecht The Netherlands"},{"name":"Department of Experimental Cardiology Erasmus Medical Center  3015 GD Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina","family":"Vermonden","sequence":"additional","affiliation":[{"name":"Division of Pharmaceutics Utrecht Institute for Pharmaceutical Sciences  3584 CG Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1560-1074","authenticated-orcid":false,"given":"Rosalinde","family":"Masereeuw","sequence":"additional","affiliation":[{"name":"Division of Pharmacology Utrecht Institute for Pharmaceutical Sciences  3584 CG Utrecht The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,8,9]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158765"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000525015.43613.75"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2015(09)01"},{"key":"e_1_2_8_4_1","first-page":"59","volume":"21","author":"Helal I.","year":"2010","journal-title":"Saudi J. 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