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Notably, myocardium has extremely limited regeneration potential due to the loss or death of cardiomyocytes (i.e., the cells of which the myocardium is comprised) upon MI. A variety of stem cells and stem cell\u2010derived cardiovascular cells, in situ cardiac fibroblasts and endogenous proliferative epicardium, have been exploited to provide renewable cellular sources to treat injured myocardium. Also, different strategies, including direct injection of cell suspensions, bioactive molecules, or cell\u2010incorporated biomaterials, and implantation of artificial cardiac scaffolds (e.g., cell sheets and cardiac patches), have been developed to deliver renewable cells and\/or bioactive molecules to the MI site for the myocardium regeneration. This article briefly surveys cell sources and delivery strategies, along with biomaterials and their processing techniques, developed for MI treatment. Key issues and challenges, as well as recommendations for future research, are also discussed.<\/jats:p>","DOI":"10.1002\/adhm.202001175","type":"journal-article","created":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T03:53:55Z","timestamp":1601524435000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Cardiomyocyte Induction and Regeneration for Myocardial Infarction Treatment: Cell Sources and Administration Strategies"],"prefix":"10.1002","volume":"9","author":[{"given":"Lihong","family":"He","sequence":"first","affiliation":[{"name":"Department of Cell Biology Medical College of Soochow University  Suzhou 215123 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4716-549X","authenticated-orcid":false,"given":"Xiongbiao","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering Division of Biomedical Engineering University of Saskatchewan  Saskatoon S7N5A9 Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07060"},{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature06969"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164680"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00630-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2017.106"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.11.042"},{"key":"e_1_2_8_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2017.100"},{"key":"e_1_2_8_5_3","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2017.38"},{"key":"e_1_2_8_5_4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.05.009"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/292154a0"},{"key":"e_1_2_8_6_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.12.7634"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90317-6"},{"key":"e_1_2_8_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/359550a0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.05.006"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2018.06.018"},{"key":"e_1_2_8_9_1","first-page":"27","volume":"87","author":"Doetschman T. 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