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In this work, a Au@Ag nanorods\u2010poly(dimethylsiloxane) (Au@Ag NRs\u2010PDMS) wearable mouthguard, which can visualize the tooth lesion sites through the color change of it at the corresponding locations, is presented. The Au@Ag NRs\u2010PDMS composite exhibits a distinct color response to hydrogen sulfide (H<jats:sub>2<\/jats:sub>S) gas generated by bacterial decay at the lesion sites. Moreover, the Au@Ag NRs\u2010PDMS mouthguard is demonstrated to own desired mechanical properties, excellent chemical stability, as well as good biocompatibility, and can accurately locate the lesion sites in human oral cavity. 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