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Central to any cell therapy is the design of delivery systems that support cell survival and integration. In T1DM, well\u2010established fabrication methods have created a wide range of implants, ranging from 3D macro\u2010scale scaffolds to nano\u2010scale coatings. These traditional methods, however, are often challenged by their inherent limitations in reproducible and discrete fabrication, particularly when scaling to the clinic. Additive manufacturing (AM) techniques provide a means to address these challenges by delivering improved control over construct geometry and microscale component placement. While still early in development in the context of T1DM cellular transplantation, the integration of AM approaches serves to improve nutrient material transport, vascularization efficiency, and the accuracy of cell, matrix, and local therapeutic placement. 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