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Thus, skincare should be taken very seriously, especially by patients with sensory disorders. However, currently available skin\u2010mimicking devices are always limited by so much insufficient response functions and nontunable interface behaviors so as not to realize precise health monitoring and self\u2010defense against injury. Herein, a bioinspired cutaneous receptor\u2010perceptual system (CRPS) patch is presented, integrating hybrid pH indicators and triboelectric nanogenerators into biointerface film\u2010adhesives that are fabricated through facile layer\u2010by\u2010layer (LBL) self\u2010assembly of amide and Schiff\u2010base linkages between alginate grafted with N\u2010hydroxysuccinimide ester (AN), tannic acid (TA), and polyethylenimine (PEI). This CRPS patch is adhered robustly to the soft\u2010curved skin surface without failure via \u201cmolecular suturing,\u201d and amino acid enables its benign peel\u2010on\u2010demand from tissue interfaces. Postdamage self\u2010healing brings it without surgical reoperation, avoiding extra cost, pain, as well as infection risks. Significantly, CRPS patches as artificial chemo\/mechanoreceptors can remotely visualize skin physiological status by pH\u2010induced chromism using smartphones and prevent skin contact injury by tactility\u2010driven self\u2010powered electrical signals. Overall, the LBL\u2010based strategy to create controllably biointerface\u2010adhesive CRPS patches will usher in a new era of the mobihealth care platform supporting smart diagnosis and self\u2010protection.<\/jats:p>","DOI":"10.1002\/adhm.202202296","type":"journal-article","created":{"date-parts":[[2022,11,15]],"date-time":"2022-11-15T03:00:10Z","timestamp":1668481210000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["LBL Noninvasively Peelable Biointerfacial Adhesives for Cutaneo\u2010Inspired pH\/Tactility Artificial Receptors"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1487-4812","authenticated-orcid":false,"given":"Renqiang","family":"Yuan","sequence":"first","affiliation":[{"name":"State Key Laboratory of Bioelectronics School of Biological Science and Medical Engineering Southeast University  Nanjing 210096 P. R. 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