{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:14:08Z","timestamp":1790014448868,"version":"4.0.1"},"reference-count":45,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100008250","name":"Shaanxi University of Science and Technology","doi-asserted-by":"publisher","award":["KFKT2022\u201011"],"award-info":[{"award-number":["KFKT2022\u201011"]}],"id":[{"id":"10.13039\/501100008250","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22278257"],"award-info":[{"award-number":["22278257"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Electronic skins (e\u2010skins) have the potential to turn into breakthroughs in biomedical applications. Herein, a novel acellular dermal matrix (ADM)\u2010based bioelectronic skin (e\u2010ADM) is used to fabricate versatile \u201cwound therapy\u2010health monitoring\u201d tissue\u2010nanoengineered skin scaffolds via a facile \u201cone\u2010pot\u201d bio\u2010compositing strategy to incorporate the conductive carbon nanotubes and self\u2010assembled micro\u2010copper oxide microspheres with a cicada\u2010wing\u2010like rough surface and nanocone microstructure. The e\u2010ADM exhibits robust tensile strength (22\u00a0MPa), flexibility, biodegradability, electroactivity, and antibacterial properties. Interestingly, e\u2010ADM exhibits the pH\u2010responsive ability for intelligent command between sterilization and wound repair . Additionally, e\u2010ADM enables accurate real\u2010time monitoring of human activities, providing a novel flexible e\u2010skin sensor to record injury and motions. In vitro and in vivo experiments show that with electrical stimulation, e\u2010ADM could prominently facilitate cell growth and proliferation and further promote full\u2010thickness skin wound healing, providing a comprehensive therapeutic strategy for smart sensing and tissue repair, guiding the development of high\u2010performance \u201cwound therapy\u2010health monitoring\u201d bioelectronic skin\u2010scaffolds.<\/jats:p>","DOI":"10.1002\/adhm.202202971","type":"journal-article","created":{"date-parts":[[2023,3,22]],"date-time":"2023-03-22T09:30:15Z","timestamp":1679477415000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Nature\u2010Skin\u2010Derived e\u2010Skin as Versatile \u201cWound Therapy\u2010Health Monitoring\u201d Bioelectronic Skin\u2010Scaffolds: Skin to Bio\u2010e\u2010Skin"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0286-2061","authenticated-orcid":false,"given":"Xinhua","family":"Liu","sequence":"first","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"},{"name":"College of Chemistry and Chemical Engineering Shaanxi University of Science &amp; Technology  Xi'an Shaanxi 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boqiang","family":"Cui","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuechuan","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"},{"name":"College of Chemistry and Chemical Engineering Shaanxi University of Science &amp; Technology  Xi'an Shaanxi 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manhui","family":"Zheng","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongxue","family":"Bai","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ouyang","family":"Yue","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering Shaanxi University of Science &amp; Technology  Xi'an Shaanxi 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Fei","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huie","family":"Jiang","sequence":"additional","affiliation":[{"name":"College of Bioresources Chemical and Materials Engineering Institute of Biomass &amp; Functional Materials Shaanxi University of Science &amp; Technology  Xi'an 710021 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201901924"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201905767"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2017.228"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/srt.12424"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1210-1079"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24382-4"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioadv.2022.212790"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201901041"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ab7cfc"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201601177"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121026"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmt.2022.101576"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2018.01.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202007429"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.0c00767"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201901474"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2019.04.001"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1109\/JSEN.2021.3061949"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/ac451e"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surfin.2021.100995"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compscitech.2021.108738"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c00420"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2018.10.036"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtv.2021.09.003"},{"key":"e_1_2_7_25_1","first-page":"1","volume":"2012","author":"Loren P.","year":"2021","journal-title":"Oxid. Med. Cell Longevity"},{"key":"e_1_2_7_26_1","volume":"136","author":"Capella\u2010Monson\u00eds H.","year":"2020","journal-title":"Mater. Today Bio"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s42825-020-00046-9"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c22746"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2019.10.045"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00118"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.07.062"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.5b08309"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8TB03295E"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.8b01092"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.2c02540"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.2c00559"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201602790"},{"key":"e_1_2_7_38_1","first-page":"490","volume":"562","author":"Fu X. M.","year":"2012","journal-title":"Adv. Mater."},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.5b00382"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.129478"},{"key":"e_1_2_7_41_1","volume":"21","author":"Liu H.","year":"2019","journal-title":"Mater. Today Commun."},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b16078"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c00749"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112567"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aba9624"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202202971","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202202971","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T11:36:52Z","timestamp":1759750612000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202202971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,10]]},"references-count":45,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1002\/adhm.202202971"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202202971","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,10]]},"assertion":[{"value":"2022-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2202971"}}