{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:08:16Z","timestamp":1792688896814,"version":"4.5.0"},"reference-count":175,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2023,5,14]],"date-time":"2023-05-14T00:00:00Z","timestamp":1684022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21975246"],"award-info":[{"award-number":["21975246"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51903233"],"award-info":[{"award-number":["51903233"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52103193"],"award-info":[{"award-number":["52103193"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52273124"],"award-info":[{"award-number":["52273124"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Platinum drugs with manifest therapeutic effects are widely used, but their systemic toxicity and the drug resistance acquired by cancer cells limit their clinical applications. Thus, the exploration on appropriate methods and strategies to overcome the limitations of traditional platinum drugs becomes extremely necessary. Combination therapy of platinum drugs can inhibit tumor growth and metastasis in an additive or synergistic manner, and can potentially reduce the systemic toxicity of platinum drugs and overcome platinum\u2010resistance. This review summarizes the various modalities and current progress in platinum\u2010based combination therapy. The synthetic strategies and therapeutic effects of some platinum\u2010based anticancer complexes in the combination of platinum drugs with gene editing, ROS\u2010based therapy, thermal therapy, immunotherapy, biological modelling, photoactivation, supramolecular self\u2010assembly and imaging modality are briefly described. Their potential challenges and prospects are also discussed. It is hoped that this review will inspire researchers to have more ideas for the future development of highly effective platinum\u2010based anti\u2010cancer complexes.<\/jats:p>","DOI":"10.1002\/adhm.202300253","type":"journal-article","created":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T11:50:21Z","timestamp":1682423421000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":70,"title":["Recent Advances of Platinum\u2010Based Anticancer Complexes in Combinational Multimodal Therapy"],"prefix":"10.1002","volume":"12","author":[{"given":"Tianyuan","family":"Zhong","sequence":"first","affiliation":[{"name":"Faculty of Chemistry Northeast Normal University  Changchun 130024 China"},{"name":"Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Northeast Normal University  Changchun 130024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Yu","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry Northeast Normal University  Changchun 130024 China"},{"name":"Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Northeast Normal University  Changchun 130024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Pan","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry Northeast Normal University  Changchun 130024 China"},{"name":"Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Northeast Normal University  Changchun 130024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Second Affiliated Hospital of Harbin Medical University Department of Orthopedics  Harbin 150000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxin","family":"Qi","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry Northeast Normal University  Changchun 130024 China"},{"name":"Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Northeast Normal University  Changchun 130024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5212-318X","authenticated-orcid":false,"given":"Yubin","family":"Huang","sequence":"additional","affiliation":[{"name":"Faculty of Chemistry Northeast Normal University  Changchun 130024 China"},{"name":"Key Laboratory of Sustainable Advanced Functional Materials of Jilin Province Northeast Normal University  Changchun 130024 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,14]]},"reference":[{"key":"e_1_2_15_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1566"},{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-6611"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2167"},{"key":"e_1_2_15_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-00308-y"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00048279"},{"key":"e_1_2_15_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/med.21360"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/ed083p728"},{"key":"e_1_2_15_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2009.01.028"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00597"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr4004314"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja071143p"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2014.05.002"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c00950"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5829.2007.00142.x"},{"key":"e_1_2_15_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.1997.tb00270.x"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2015.11.003"},{"key":"e_1_2_15_12_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01351"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2018.07.004"},{"key":"e_1_2_15_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2021.214210"},{"key":"e_1_2_15_14_1","first-page":"20","author":"Vaughan H. J.","year":"2021","journal-title":"Curr. Opin. Biomed. Eng."},{"key":"e_1_2_15_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008386"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2019.01.020"},{"key":"e_1_2_15_15_2","doi-asserted-by":"publisher","DOI":"10.1039\/C9QI00288J"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4BM00272E"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.05.049"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201706220"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0NH00148A"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtchem.2021.100740"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201303360"},{"key":"e_1_2_15_22_1","first-page":"1","volume-title":"Current Advances in Osteosarcoma: Clinical Perspectives: Past, Present and Future","author":"Benjamin R. S.","year":"2020"},{"key":"e_1_2_15_22_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363190-00013"},{"key":"e_1_2_15_23_1","first-page":"13, 67","author":"Zhang H.","year":"2020","journal-title":"Polymers (Basel)"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201507281"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.06.004"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TB00178A"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912276106"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.05.047"},{"key":"e_1_2_15_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201300402"},{"key":"e_1_2_15_28_3","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201200385"},{"key":"e_1_2_15_28_4","doi-asserted-by":"publisher","DOI":"10.1039\/C4BM00305E"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.6b00236"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB02583J"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.11.006"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB01222C"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR03693C"},{"key":"e_1_2_15_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2015.03.029"},{"key":"e_1_2_15_33_3","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201500080"},{"key":"e_1_2_15_33_4","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201500379"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7TB01704A"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1067\/j.cpsurg.2009.09.003"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25989"},{"key":"e_1_2_15_36_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-020-3124-y"},{"key":"e_1_2_15_36_3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c03127"},{"key":"e_1_2_15_36_4","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c05541"},{"key":"e_1_2_15_36_5","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2021.02.001"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.10.060"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA17230F"},{"key":"e_1_2_15_38_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.05.046"},{"key":"e_1_2_15_38_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2015.03.001"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-16-1536"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201803217"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2021.130377"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b12108"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b04981"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202102494"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-013-0591-8"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.68.4.820"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.3121\/cmr.4.3.218"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.11.014"},{"key":"e_1_2_15_48_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.120577"},{"key":"e_1_2_15_48_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.09.017"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b00083"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0973-6"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-020-3066-4"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.11.015"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2018.11.001"},{"key":"e_1_2_15_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1894"},{"key":"e_1_2_15_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202002178"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201600124"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1071"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c09555"},{"key":"e_1_2_15_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.135993"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201400533"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202106100"},{"key":"e_1_2_15_61_1","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2014.992484"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202000326"},{"key":"e_1_2_15_63_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.58755"},{"key":"e_1_2_15_63_2","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202103528"},{"key":"e_1_2_15_63_3","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S208404"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202101467"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121428"},{"key":"e_1_2_15_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2015.218"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2022.109423"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202107656"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.01.004"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.1667\/0033-7587(2002)157[0032:EOXRIB]2.0.CO;2"},{"key":"e_1_2_15_70_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm061416b"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp400852p"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202106388"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.34356"},{"key":"e_1_2_15_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.042"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2021.101977"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2016.572"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2022.101459"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2018.12.007"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2014.1758"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2384"},{"key":"e_1_2_15_81_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9081775"},{"key":"e_1_2_15_82_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1708618"},{"key":"e_1_2_15_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202100599"},{"key":"e_1_2_15_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.05.030"},{"key":"e_1_2_15_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202201486"},{"key":"e_1_2_15_86_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b00021"},{"key":"e_1_2_15_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201602738"},{"key":"e_1_2_15_87_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202202245"},{"key":"e_1_2_15_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.121917"},{"key":"e_1_2_15_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.03.077"},{"key":"e_1_2_15_89_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201601058"},{"key":"e_1_2_15_90_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c10732"},{"key":"e_1_2_15_90_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.03.035"},{"key":"e_1_2_15_91_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.12.024"},{"key":"e_1_2_15_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201703408"},{"key":"e_1_2_15_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.135711"},{"key":"e_1_2_15_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1011-1344(00)00082-8"},{"key":"e_1_2_15_95_1","first-page":"15, 480","author":"Qu Y.","year":"2022","journal-title":"Pharmaceuticals"},{"key":"e_1_2_15_96_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0177049"},{"key":"e_1_2_15_97_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c21349"},{"key":"e_1_2_15_98_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.2c00608"},{"key":"e_1_2_15_99_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC03692E"},{"key":"e_1_2_15_100_1","first-page":"25, 5167","author":"Dai Z.","year":"2020","journal-title":"Molecules"},{"key":"e_1_2_15_101_1","first-page":"155","volume":"11","author":"Kratochwil N. A.","year":"1996","journal-title":"Anticancer Drug Des."},{"key":"e_1_2_15_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.197805241"},{"key":"e_1_2_15_103_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5TB00576K"},{"key":"e_1_2_15_103_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201307505"},{"key":"e_1_2_15_103_3","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA26372G"},{"key":"e_1_2_15_104_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0TB01103G"},{"key":"e_1_2_15_105_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1BM01154E"},{"key":"e_1_2_15_106_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9DT01645G"},{"key":"e_1_2_15_106_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201906203"},{"key":"e_1_2_15_106_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.05.052"},{"key":"e_1_2_15_107_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b02346"},{"key":"e_1_2_15_107_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.10.020"},{"key":"e_1_2_15_107_3","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC06839J"},{"key":"e_1_2_15_108_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00221"},{"key":"e_1_2_15_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2019.08.021"},{"key":"e_1_2_15_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202008604"},{"key":"e_1_2_15_110_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202102739"},{"key":"e_1_2_15_110_3","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202201178"},{"key":"e_1_2_15_111_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c01676"},{"key":"e_1_2_15_111_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201800422"},{"key":"e_1_2_15_111_3","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR04213G"},{"key":"e_1_2_15_112_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR03288G"},{"key":"e_1_2_15_113_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c11327"},{"key":"e_1_2_15_114_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1252510"},{"key":"e_1_2_15_115_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.7b01193"},{"key":"e_1_2_15_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202203838"},{"key":"e_1_2_15_117_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202101826"},{"key":"e_1_2_15_118_1","first-page":"12, 604","author":"Hong S.","year":"2020","journal-title":"Pharmaceutics"},{"key":"e_1_2_15_119_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c10770"},{"key":"e_1_2_15_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2021.106000"},{"key":"e_1_2_15_121_1","unstructured":"M.Magnani L.Rossi L.Chiarantini A.Fraternale A.Casabianca inNATO Advanced Institute on Targeting of Drugs \u2013 Advances in System Constructs Cape Sounion Greece1994."},{"key":"e_1_2_15_122_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC02941J"},{"key":"e_1_2_15_123_1","first-page":"14","author":"Wen X.","year":"2023","journal-title":"Nat. Commun."},{"key":"e_1_2_15_123_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121867"},{"key":"e_1_2_15_123_3","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202202135"},{"key":"e_1_2_15_124_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b03476"},{"key":"e_1_2_15_124_2","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201201746"},{"key":"e_1_2_15_124_3","doi-asserted-by":"publisher","DOI":"10.1021\/ic401060k"},{"key":"e_1_2_15_124_4","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202101199"},{"key":"e_1_2_15_125_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8TB01034J"},{"key":"e_1_2_15_125_2","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202100938"},{"key":"e_1_2_15_125_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120478"},{"key":"e_1_2_15_126_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201301713"},{"key":"e_1_2_15_127_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c01764"},{"key":"e_1_2_15_128_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.22172"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202300253","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T19:05:22Z","timestamp":1759777522000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202300253"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,14]]},"references-count":175,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1002\/adhm.202300253"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202300253","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,14]]},"assertion":[{"value":"2023-01-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2300253"}}