{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T06:22:45Z","timestamp":1791872565108,"version":"4.3.4"},"reference-count":35,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2024,4,4]],"date-time":"2024-04-04T00:00:00Z","timestamp":1712188800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21874078"],"award-info":[{"award-number":["21874078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22074072"],"award-info":[{"award-number":["22074072"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22274083"],"award-info":[{"award-number":["22274083"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2022LZY022"],"award-info":[{"award-number":["ZR2022LZY022"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2023LZY005"],"award-info":[{"award-number":["ZR2023LZY005"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The synthesis of water\u2010soluble symmetric molecules with donor\u2010acceptor\u2010donor (D\u2010A\u2010D) structure is reported. The compound is connected by \u03c0 bridge with 2\u2010bromofluorene external polyethylene glycol 2000 as the shielding unit, and donor component and pyrrolopyrrole (DPP) as the acceptor unit. The D\u2010A\u2010D double donor fluorescent molecule P2\u2010DPP is obtained by coupling reaction. The absorption peak and emission peak of the fluorescent molecule P2\u2010DPP are 600 and 1020 nm, respectively. It has potential excellent imaging characteristics. It does not need to use nanoparticles formed by the DSPE\u2010MPEG amphiphilic block to form micelles. The quantum yield reaches 0.6% and the penetration depth can reach 10 mm. The chemical is capable of achieving liver and renal metabolism. It has a good application prospect in the photothermal therapy of mouse tumors and realizes the integration of biological diagnosis and treatment.<\/jats:p>","DOI":"10.1002\/adhm.202304564","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T19:58:45Z","timestamp":1711742325000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Synthesis on NIR\u2010II Multifunctional Imaging and Photothermal Therapy of a Novel Water\u2010Soluble Molecule"],"prefix":"10.1002","volume":"13","author":[{"given":"Mengyu","family":"Cao","sequence":"first","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wentao","family":"Zou","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2932-1118","authenticated-orcid":false,"given":"Bing","family":"Yu","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"},{"name":"State Key Laboratory of Bio\u2010Fibers and Eco\u2010Textiles Qingdao University  Qingdao 266071 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hailin","family":"Cong","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"},{"name":"State Key Laboratory of Bio\u2010Fibers and Eco\u2010Textiles Qingdao University  Qingdao 266071 China"},{"name":"School of Materials Science and Engineering Shandong University of Technology  Zibo 255000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youqing","family":"Shen","sequence":"additional","affiliation":[{"name":"College of Chemistry and Chemical Engineering College of Materials Science and Engineering Institute of Biomedical Materials and Engineering Qingdao University  Qingdao 266071 China"},{"name":"Key Laboratory of Biomass Chemical Engineering of Ministry of Education Center for Bionanoengineering and Department of Chemical and Biological Engineering Zhejiang University  Hangzhou Zhejiang 310027 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,4]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.201800075"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.2c00643"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.09.004"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pacs.2022.100426"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.114697"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114637"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR00305J"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-019-9685-6"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2023.101795"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.04.024"},{"key":"e_1_2_8_11_1","volume":"468","author":"Cong H.","year":"2022","journal-title":"SSRN Electron. J."},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202008123"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41377-021-00628-0"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2018.07.004"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201500010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202006891"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1705"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202208028"},{"key":"e_1_2_8_19_1","first-page":"2161","volume":"322","author":"Abbasi J.","year":"2019","journal-title":"JAMA, J. Am. Med. Assoc."},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202207318"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4476"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15269"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201600013"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b07020"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10853-020-04800-6"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3TA13816J"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b07927"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.08.007"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202111052"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b09025"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b06866"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2BM01912D"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202101697"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120717"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(86)90215-2"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202304564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T14:39:13Z","timestamp":1759761553000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202304564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,4]]},"references-count":35,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/adhm.202304564"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202304564","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,4]]},"assertion":[{"value":"2023-12-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2304564"}}