{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T16:41:21Z","timestamp":1781714481317,"version":"3.54.5"},"reference-count":73,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T00:00:00Z","timestamp":1710979200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22175037"],"award-info":[{"award-number":["22175037"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52103108"],"award-info":[{"award-number":["52103108"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51773038"],"award-info":[{"award-number":["51773038"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Emergency prehospital wound closure and hemorrhage control are the first priorities for life\u2010saving. Majority of bioadhesives form bonds with tissues through irreversible cross\u2010linking, and the remobilization of misalignment may cause severe secondary damage to tissues. Therefore, developing an adhesive that can quickly and tolerably adhere to traumatized dynamic tissue or organ surfaces in emergency situations is a major challenge. Inspired by the structure of human serum albumin (HSA), a branched polymer with multitentacled sulfhydryl is synthesized, then, an instant and fault\u2010tolerant tough wet\u2010tissue adhesion (IFA) hydrogel is prepared. Adhesive application time is just 5 s (interfacial toughness of \u2248580 J m<jats:sup>\u22122<\/jats:sup>), and favorable tissue\u2010adhesion is maintained after ten cycles. IFA hydrogel shows unchangeable adhesive performance after 1 month of storage based on the internal oxidation\u2013reduction mechanism. It not only can efficiently seal various organs but also achieves effective hemostasis in models of the rat femoral artery and rabbit\u2010ear artery. This work also proposes an effective strategy for controllable adhesion, enabling the production of asymmetric adhesives with on\u2010demand detachment. Importantly, IFA hydrogel has sound antioxidation, antibacterial property, hemocompatibility, and cytocompatibility. Hence, the HSA\u2010inspired bioadhesive emerges as a promising first\u2010aid supply for human\u2013machine interface\u2010based health management and non\u2010invasive wound closure.<\/jats:p>","DOI":"10.1002\/adhm.202400033","type":"journal-article","created":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T09:25:08Z","timestamp":1710408308000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Ferried Albumin\u2010Inspired Bioadhesive With Dynamic Interfacial Bonds for Emergency Rescue"],"prefix":"10.1002","volume":"13","author":[{"given":"Yiming","family":"Chen","sequence":"first","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiying","family":"Li","sequence":"additional","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renfeng","family":"Xu","sequence":"additional","affiliation":[{"name":"College of Life Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Fang","sequence":"additional","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinhui","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengchao","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Life Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiqing","family":"Liu","sequence":"additional","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9208-8289","authenticated-orcid":false,"given":"Yunxiang","family":"Weng","sequence":"additional","affiliation":[{"name":"College of Chemistry and Materials Science Fujian Normal University  Fujian 350117 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,21]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201700859"},{"key":"e_1_2_8_1_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28209-8"},{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-019-0171-7"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00815"},{"key":"e_1_2_8_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.11.008"},{"key":"e_1_2_8_3_3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10004-7"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1710-5"},{"key":"e_1_2_8_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-022-00905-2"},{"key":"e_1_2_8_4_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122240"},{"key":"e_1_2_8_4_4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.12.003"},{"key":"e_1_2_8_4_5","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201907064"},{"key":"e_1_2_8_4_6","doi-asserted-by":"publisher","DOI":"10.1016\/j.compositesb.2021.109525"},{"key":"e_1_2_8_4_7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.135808"},{"key":"e_1_2_8_4_8","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c11053"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00798"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29427-w"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4906"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201704640"},{"key":"e_1_2_8_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202102983"},{"key":"e_1_2_8_8_3","doi-asserted-by":"publisher","DOI":"10.1039\/D0MH01231A"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abi9702"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202007663"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202212302"},{"key":"e_1_2_8_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-27529-5"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119289"},{"key":"e_1_2_8_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cis.2017.06.012"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-020-01204-7"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2016.1193149"},{"key":"e_1_2_8_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c09334"},{"key":"e_1_2_8_14_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.142432"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lwt.2021.112537"},{"key":"e_1_2_8_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1437"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0GC02909B"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2GC04185E"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202001122"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119905"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.3c00159"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2023.08.021"},{"key":"e_1_2_8_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202214148"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-06037-0"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202111465"},{"key":"e_1_2_8_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.09.002"},{"key":"e_1_2_8_23_3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2006389117"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40856-z"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2207422119"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c01976"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(90)90018-X"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11409"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-14446-2"},{"key":"e_1_2_8_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202111747"},{"key":"e_1_2_8_29_3","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201604827"},{"key":"e_1_2_8_29_4","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-023-01096-4"},{"key":"e_1_2_8_29_5","doi-asserted-by":"publisher","DOI":"10.1038\/347455a0"},{"key":"e_1_2_8_29_6","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c04781"},{"key":"e_1_2_8_29_7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.0c02941"},{"key":"e_1_2_8_29_8","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg2689"},{"key":"e_1_2_8_29_9","doi-asserted-by":"publisher","DOI":"10.5254\/1.3538750"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202301913"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aai7466"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2GC04333E"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00750"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202108992"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202210395"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202100093"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c21839"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c07492"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b08969"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.1c00335"},{"key":"e_1_2_8_40_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202302943"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adf8645"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201605350"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adg3229"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202009442"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202400033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T16:28:18Z","timestamp":1759768098000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202400033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,21]]},"references-count":73,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/adhm.202400033"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202400033","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,21]]},"assertion":[{"value":"2024-01-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2400033"}}