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Here, an H\n                    <jats:sub>2<\/jats:sub>\n                    S harvester nanosystem to prevent the generation of persister bacteria and disrupt the dense biofilm matrix by the self\u2010adaptive ability of shape\u2010morphing is prepared. The nanosystem possesses a core\u2010shell structure that is composed of liquid metal nanoparticle (LM NP), AgNPs, and immobilized urease. The nanosystem decomposes urea contained in urine to generate ammonia for eliminating bacteria\u2010derived H\n                    <jats:sub>2<\/jats:sub>\n                    S. Depending on the oxidative layer of liquid metal, the nanosystem also constitutes a long\u2010lasting reservoir for temporarily storing bacteria\u2010derived H\n                    <jats:sub>2<\/jats:sub>\n                    S, when urease transiently overloads or in the absence of urine in a catheter. Depriving H\n                    <jats:sub>2<\/jats:sub>\n                    S can prevent the emergence of persistent bacteria, enhancing the bacteria\u2010killing efficiency of Ga\n                    <jats:sup>3+<\/jats:sup>\n                    and Ag\n                    <jats:sup>+<\/jats:sup>\n                    ions. Even when the biofilm has formed, the urine flow provides heat to trigger shape morphing of the LM NP, tearing the biofilm matrix. Collectively, this strategy can turn trash (urea) into treasure (H\n                    <jats:sub>2<\/jats:sub>\n                    S scavengers and biofilm rippers), and provides a new direction for the antibacterial materials application in the medical field.\n                  <\/jats:p>","DOI":"10.1002\/adhm.202401067","type":"journal-article","created":{"date-parts":[[2024,7,19]],"date-time":"2024-07-19T04:17:33Z","timestamp":1721362653000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Trash into Treasure: Nano\u2010coating of Catheter Utilizes Urine to Deprive H\n                    <sub>2<\/sub>\n                    S Against Persister and Rip Biofilm Matrix"],"prefix":"10.1002","volume":"13","author":[{"given":"Zhiming","family":"Hou","sequence":"first","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinyu","family":"Ren","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuangzhuang","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruoqi","family":"An","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingzhi","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cen","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. 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China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dengqi","family":"He","sequence":"additional","affiliation":[{"name":"Department of Stomatology The First Hospital of Lanzhou University  Lanzhou 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongliang","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Stomatology The First Hospital of Lanzhou University  Lanzhou 730000 P. R. China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7938-0370","authenticated-orcid":false,"given":"Rongbing","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Stomatology Lanzhou University  Lanzhou 730000 P. R. China"},{"name":"Key Laboratory of Dental Maxillofacial Reconstruction and Biological Intelligence Manufacturing  Lanzhou Gansu 730000 P. R. 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