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Near\u2010infrared (NIR)\u2010II fluorescence imaging offers advantages such as deep tissue penetration, real\u2010time visualization, and a high signal\u2010to\u2010background ratio, making it highly suitable for diagnosing hemorrhagic diseases. In this study, an NIR\u2010II fluorescent probe LJ\u20102P carrying carboxylic and phosphoric acid groups is successfully applied for imaging hemorrhagic diseases. LJ\u20102P demonstrates a strong affinity for fibrinogen and fibrin clots both computationally and experimentally, thus exhibiting increased brightness upon coagulation. As compared to Indocyanine Green, LJ\u20102P provides a longer imaging window, higher imaging specificity, and signal\u2010to\u2010background ratio, as well as superior photobleaching resistance in three disease models: gastric, pulmonary, and cerebral hemorrhages. 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