{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T18:28:34Z","timestamp":1775586514092,"version":"3.50.1"},"reference-count":77,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T00:00:00Z","timestamp":1730160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22178140"],"award-info":[{"award-number":["22178140"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22075011"],"award-info":[{"award-number":["22075011"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170994"],"award-info":[{"award-number":["82170994"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Efficient personal protection has emerged as a crucial approach for reducing pulmonary injury induced by particulate matter (PM). However, current personal protective equipments usually lack essential biosafety concerns and fail to own adsorbing\/antioxidant\/antibacterial function together, making it a challenge to develop an integrated platform with the above characteristics. Herein, a facile oxygen\u2010free hydrothermal strategy is proposed to synthesize new copper\u2010based metal\u2010organic frameworks, Cu\u2010HHTPs, (HHTP: 2,3,6,7,10,11\u2010hexahydroxytriphenylene), with great adsorbing\/antioxidant\/antibacterial activity and high biosafety. The Cu\u2010HHTPs can serve as an efficient additive incorporated with various fabrics including cellulose acetate (CA) membrane to achieve novel fabric composites, such as CA@Cu\u2010HHTPs, with ideal scavenging outcome for the main components of PM. Evidenced by the animal experiments, CA@Cu\u2010HHTPs can highly mitigate PM\u2010induced adverse effects via adsorbing PM, scavenging ROS, and killing bacteria, leading to a significant reduction in lung permeability, inflammation and oxidative stress, and pulmonary infection. Last but not least, a two\u2010week exposure of CA@Cu\u2010HHTPs exhibits no obvious damage toward the animals by examining their long\u2010term toxicity. Collectively, this study not only highlights the potential of Cu\u2010HHTPs as attractive additives for the preparation of fabric composites, but also lays out a new concept toward the development of new\u2010generation multifunctional personal protective equipment against PM.<\/jats:p>","DOI":"10.1002\/adhm.202403061","type":"journal-article","created":{"date-parts":[[2024,10,29]],"date-time":"2024-10-29T07:48:38Z","timestamp":1730188118000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Biocompatible Metal\u2010Organic Framework\u2010Based Fabric Composite as an Efficient Personal Protective Equipment for Particulate Matter\u2010Induced Pulmonary Injury"],"prefix":"10.1002","volume":"14","author":[{"given":"Zhen","family":"Ding","sequence":"first","affiliation":[{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Life Science and Technology Beijing University of Chemical Technology  Beijing 100029 China"},{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingfu","family":"Bao","sequence":"additional","affiliation":[{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianyan","family":"Chen","sequence":"additional","affiliation":[{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinming","family":"Zhang","sequence":"additional","affiliation":[{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengjing","family":"Xu","sequence":"additional","affiliation":[{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nan","family":"Tang","sequence":"additional","affiliation":[{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Life Science and Technology Beijing University of Chemical Technology  Beijing 100029 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Hu","sequence":"additional","affiliation":[{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1886-6457","authenticated-orcid":false,"given":"Zhen","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Life Science and Technology Beijing University of Chemical Technology  Beijing 100029 China"},{"name":"Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of Stomatology Jilin University  Changchun 130021 China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,29]]},"reference":[{"key":"e_1_2_7_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/525330a"},{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2014.10.005"},{"key":"e_1_2_7_1_3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c08888"},{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nclimate2272"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2017.02.029"},{"key":"e_1_2_7_2_3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23853-y"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-019-01960-7"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaq0524"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1108752"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1103639"},{"key":"e_1_2_7_4_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2014.10.005"},{"key":"e_1_2_7_4_4","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202101251"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms7205"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2209586119"},{"key":"e_1_2_7_5_3","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202002361"},{"key":"e_1_2_7_5_4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.4c00308"},{"key":"e_1_2_7_5_5","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202003155"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b02553"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.123479"},{"key":"e_1_2_7_6_3","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b02321"},{"key":"e_1_2_7_6_4","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201603306"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c02250"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b05983"},{"key":"e_1_2_7_7_3","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201401553"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202108951"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c04782"},{"key":"e_1_2_7_8_3","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202205010"},{"key":"e_1_2_7_8_4","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c11284"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.4c00079"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c03725"},{"key":"e_1_2_7_9_3","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202101511"},{"key":"e_1_2_7_9_4","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c03597"},{"key":"e_1_2_7_9_5","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201504572"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2902-8"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2017.08.017"},{"key":"e_1_2_7_10_3","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.1c08449"},{"key":"e_1_2_7_10_4","doi-asserted-by":"publisher","DOI":"10.1021\/es505577w"},{"key":"e_1_2_7_10_5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b02967"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8564111"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/es5059378"},{"key":"e_1_2_7_11_3","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202402633"},{"key":"e_1_2_7_11_4","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02615-0"},{"key":"e_1_2_7_11_5","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2023.114362"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201902123"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/10715760801911631"},{"key":"e_1_2_7_12_3","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202201205"},{"key":"e_1_2_7_12_4","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c15358"},{"key":"e_1_2_7_12_5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.3c02145"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202311519"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b03531"},{"key":"e_1_2_7_13_3","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b01850"},{"key":"e_1_2_7_13_4","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20210157"},{"key":"e_1_2_7_13_5","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202305076"},{"key":"e_1_2_7_13_6","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20220148"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c09663"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202007827"},{"key":"e_1_2_7_14_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202000299"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr200256v"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00113"},{"key":"e_1_2_7_15_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2020.213477"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201911543"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202404894"},{"key":"e_1_2_7_16_3","doi-asserted-by":"publisher","DOI":"10.1039\/D2SC03648G"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201808249"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.4c01189"},{"key":"e_1_2_7_17_3","author":"Liu X.","year":"2024","journal-title":"Adv. Sci."},{"key":"e_1_2_7_17_4","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20210157"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201709558"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1021\/cm301194a"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b05277"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1039\/D3QI00349C"},{"key":"e_1_2_7_19_3","doi-asserted-by":"publisher","DOI":"10.1080\/02786826.2018.1504161"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b04022"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202305133"},{"key":"e_1_2_7_20_3","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.05.026"},{"key":"e_1_2_7_20_4","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.06.060"},{"key":"e_1_2_7_20_5","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202309278"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202403061","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T18:59:25Z","timestamp":1759777165000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202403061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,29]]},"references-count":77,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["10.1002\/adhm.202403061"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202403061","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,29]]},"assertion":[{"value":"2024-08-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2403061"}}