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Compared to conventional rigid gel electrodes, stretchable electrodes are advantageous for long\u2010term monitoring with superior skin conformality. However, current devices often show limited compliance and adhesive reliability, especially during human motion. Here, a skin\u2010tailored adhesive bio\u2010electrode (STABL) is fabricated using a substrate designed to comply with the deformation behavior of wrist skin. The substrate patch possesses a negative Poisson's ratio (PR) through an auxetic structured glass fabric reinforcement embedded in a soft, adhesive elastomer film. Based on the direct measurement of wrist skin deformation behavior, the chemical composition and geometry of the substrate patch are optimized to match the negative PR of the skin. Using this tailored substrate, STABL is fabricated with EGaIn liquid metal conductors and exhibits superior stability in electrophysiology communication during repetitive wrist motion compared to conventional pristine PDMS substrates. This result highlights the potential of skin\u2010tailored auxetic substrates and liquid metal electrodes for reliable, long\u2010term wearable bioelectronics applications.<\/jats:p>","DOI":"10.1002\/adhm.202404882","type":"journal-article","created":{"date-parts":[[2025,3,11]],"date-time":"2025-03-11T18:46:55Z","timestamp":1741718815000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Skin\u2010Tailored Adhesive Bio\u2010Electrode with Tunable Poisson's Ratio for Stable Electrophysiological Communication"],"prefix":"10.1002","volume":"14","author":[{"given":"Hyun Seok","family":"Kang","sequence":"first","affiliation":[{"name":"Wearable Platform Materials Technology Center (WMC) Department of Materials Science and Engineering KAIST  Daejeon 34141 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering Yonsei University  Seoul 03722 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyunggwi","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering KAIST  Daejeon 34141 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yung","family":"Lee","sequence":"additional","affiliation":[{"name":"Wearable Platform Materials Technology Center (WMC) Department of Materials Science and Engineering KAIST  Daejeon 34141 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junho","family":"Jang","sequence":"additional","affiliation":[{"name":"Insulation Materials Research Center Electrical Materials Research Division Korea Electrotechnology Research Institute (KERI)  Changwon 51543 Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won 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