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However, it still presents some limitations, including multiple hospital visits required by the long distraction period, and previous studies show that a shortened distraction period will easily lead to a non\u2010union gap and suboptimal quality of the new bone. In this research, a 3D\u2010printed customized PGS scaffold is constructed and combined it with rapid MDO to repair mandible defects. It not only accommodates the dynamically changing distraction gap but also meets the mandibular distraction model's high morphological requirements. The BMSCs\u2010loaded PGS scaffolds also provide favorable osteogenic microenvironments. This approach helps shorten the distraction period and accelerates bone regeneration and osseointegration in the rapid distraction model of rabbit mandibles, showing promise for future clinical advancements in large\u2010scale mandibular defect repair.<\/jats:p>","DOI":"10.1002\/adhm.202405193","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T01:35:15Z","timestamp":1749519315000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["3D Printed Bioelastomer Scaffold for Mandibular Defect Repair Based on Rapid Distraction Therapy"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4468-198X","authenticated-orcid":false,"given":"Yingjie","family":"Yan","sequence":"first","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byeong Seop","family":"Kim","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojun","family":"Chen","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyi","family":"Huang","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Lin","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenqing","family":"Han","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangdong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Plastic and reconstructive surgery Shanghai Red Cross Ninth People's Hospital: Shanghai 9th Peoples Hospital Affiliated to Shanghai Jiaotong University School of Medicine  639 Zhizaoju Road Shanghai China"},{"name":"Department of Plastic and Reconstructive Surgery Shanghai Key Lab of Tissue Engineering, Shanghai 9th People's Hospital Shanghai Jiao Tong University School of Medicine  200011 Shanghai P.R. 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