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Advances in bioelectronic sutures enable monitoring and therapy, but reliance on external power or complex circuits limits their use in long\u2010term and minimally invasive applications. Herein, a self\u2010powered bioelectronic suture (B\u2010suture) is reported that enables real\u2010time tension monitoring during suturing. The B\u2010suture integrates a conductive composite within a capillary structure. Hybrid laser processing, combining continuous wave laser\u2010induced phase separation and femtosecond laser\u2010engraved microstructures, greatly enhances electro\u2010mechanical properties and triboelectric sensing performance. The triboelectric nanogenerator\u2010based principle enables tension detection in the 0\u20132\u00a0N range. In vitro and in vivo evaluations demonstrate biocompatibility and precise monitoring of suturing tightness. By providing real\u2010time quantitative feedback, the proposed B\u2010suture affords to improve wound closure quality, reduce postoperative complications, and advance bioelectronic applications in surgical practice.<\/jats:p>","DOI":"10.1002\/adhm.202501329","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T07:09:12Z","timestamp":1748243352000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["A Self\u2010Powered Bioelectronic Suture via Hybrid Laser Treatment"],"prefix":"10.1002","volume":"14","author":[{"given":"Yuhong","family":"Xu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Fluid Power and Mechatronic Systems School of Mechanical Engineering Zhejiang University  Hangzhou 310027 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianyu","family":"Li","sequence":"additional","affiliation":[{"name":"National Engineering Research Center of Innovation and Application of Minimally Invasive Instruments Sir Run Run Shaw Hospital School of Medicine Zhejiang University  Hangzhou 310016 China"},{"name":"Department of Translational Medicine &amp; 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