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Augmentation is currently performed by injecting a poly(methyl methacrylate) (PMMA) slurry of polymer, monomer, and initiator mixed with barium sulfate (BaSO\n                    <jats:sub>4<\/jats:sub>\n                    ) into the vertebrae, which then polymerizes in vivo. Herein, a solvent\u2010free polymer system using poly(allyl glycidyl ether succinate) (PAGES) is developed for vertebral augmentation. PAGES crosslinks in situ through thiol\u2010ene click chemistry with a cure time at 37\u00a0\u00b0C ranging from 17 to 53 min based on degree of polymerization and crosslinker concentration. The addition of SrCO\n                    <jats:sub>3<\/jats:sub>\n                    increased the ultimate compressive strength (\u03c3\n                    <jats:sub>max<\/jats:sub>\n                    ) of the PAGES composite to 4.4 \u00b1 0.4\u00a0MPa. Furthermore, SrCO\n                    <jats:sub>3<\/jats:sub>\n                    increases osteoblast proliferation and differentiation of mesenchymal stem cells seeded onto the surface of PAGES composite. Finally, the compressive strength of fractured vertebrae is increased in an ex vivo surrogate rabbit model when filled with injected PAGES composite, demonstrating its potential as a bone augmentation material.\n                  <\/jats:p>","DOI":"10.1002\/adhm.202501633","type":"journal-article","created":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T11:01:13Z","timestamp":1751194873000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Injectable, Solvent Free Strontium Carbonate Poly(Allyl Glycidyl Ether Succinate) Composite Networks for Vertebral Augmentation"],"prefix":"10.1002","volume":"14","author":[{"given":"Russell E.","family":"Thompson","sequence":"first","affiliation":[{"name":"Department of Radiology Duke University  Durham NC 27710 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maddison I.","family":"Segal","sequence":"additional","affiliation":[{"name":"Thomas Lord Department of Mechanical Engineering &amp; Material Science Duke University  Durham NC 27708 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Sipics","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Duke University  Durham NC 27705 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola G.","family":"Judge","sequence":"additional","affiliation":[{"name":"Department of Chemistry Duke University  Durham NC 27708 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexia","family":"Bensoussan","sequence":"additional","affiliation":[{"name":"Department of Chemistry Duke University  Durham NC 27708 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bavand","family":"Keshavarz","sequence":"additional","affiliation":[{"name":"Thomas Lord Department of Mechanical Engineering &amp; Material Science Duke University  Durham NC 27708 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4089-6916","authenticated-orcid":false,"given":"Matthew L.","family":"Becker","sequence":"additional","affiliation":[{"name":"Thomas Lord Department of Mechanical Engineering &amp; Material Science Duke University  Durham NC 27708 USA"},{"name":"Department of Biomedical Engineering Duke University  Durham NC 27705 USA"},{"name":"Department of Chemistry Duke University  Durham NC 27708 USA"},{"name":"Department of Orthopedic Surgery Duke University  Durham NC 27708 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,18]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2022.02.035"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-022-04092-8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2012.08.010"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1749-799X-6-43"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A6367"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.36076\/ppj.2015\/18\/E1101"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2022.02.052"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820180411"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.2002.17.9.1621"},{"key":"e_1_2_9_10_1","first-page":"2142","volume":"24","author":"K\u0131rcelli A.","year":"2018","journal-title":"Int. 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