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Hench's discovery that certain SiO\n                    <jats:sub>2<\/jats:sub>\n                    ;\u2010based glasses can bond with bone tissue, bioactive glasses (BGs) like Bioglass 45S5 have played a key role in orthopedic, dental, and periodontal treatments. The introduction of sol\u2013gel chemistry in 1991 significantly enhanced their surface area and porosity, boosting their bioactivity and osteogenic properties. More recently, a third\u2010generation biomaterial, such as bioactive mesoporous glasses (MBGs) has emerged. Synthesized using structure\u2010directing agents, MBGs possess highly ordered pore structures and greatly increased surface areas, making them excellent carriers for therapeutic agents like antibiotics and bone\u2010regenerating compounds. Their ability to promote tissue healing and gradually resorb in the body adds to their appeal in regenerative medicine. 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MBGs thus represent a versatile and expanding class of materials in biomedical innovation.\n                  <\/jats:p>","DOI":"10.1002\/adhm.202502201","type":"journal-article","created":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T10:42:51Z","timestamp":1754908971000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery"],"prefix":"10.1002","volume":"15","author":[{"given":"Natividad","family":"G\u00f3mez\u2010Cerezo","sequence":"first","affiliation":[{"name":"Departamento de Qu\u00edmica en Ciencias Farmac\u00e9uticas Universidad Complutense de Madrid  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre i+12  Plaza Ram\u00f3n y Cajal s\/n Madrid 28040 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lozano","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica en Ciencias Farmac\u00e9uticas Universidad Complutense de Madrid  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre i+12  Plaza Ram\u00f3n y Cajal s\/n Madrid 28040 Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red  CIBER\u2010BBN Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio J.","family":"Salinas","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica en Ciencias Farmac\u00e9uticas Universidad Complutense de Madrid  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre i+12  Plaza Ram\u00f3n y Cajal s\/n Madrid 28040 Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red  CIBER\u2010BBN Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6104-4889","authenticated-orcid":false,"given":"Mar\u00eda","family":"Vallet\u2010Reg\u00ed","sequence":"additional","affiliation":[{"name":"Departamento de Qu\u00edmica en Ciencias Farmac\u00e9uticas Universidad Complutense de Madrid  Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Hospital 12 de Octubre i+12  Plaza Ram\u00f3n y Cajal s\/n Madrid 28040 Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red  CIBER\u2010BBN Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,11]]},"reference":[{"key":"e_1_2_12_1_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820050611"},{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-006-0432-z"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnoncrysol.2015.03.025"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijag.12028"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1151-2916.1991.tb07132.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/c3ra00166k"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/jab.770020403"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ejic.200390134"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.08.023"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm001107o"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011249330581"},{"key":"e_1_2_12_12_1","first-page":"260","volume":"60","author":"Nakamura T.","year":"1982","journal-title":"Bull. 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