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Curcumin (Cur), a natural diketone compound, holds therapeutic potential in treating infected wounds. However, its application is limited by poor aqueous dispersibility and low stability. To overcome this dilemma, a versatile capsule as an effective Cur carrier is developed by encapsulating Cur in succinic acid\u2010modified cyclodextrin via hydrophobic interactions, and then loading it into a Zn\n                    <jats:sup>2+<\/jats:sup>\n                    \u2010mediated crosslinked injectable hydrogel for infected wound healing. The composite hydrogel exhibits adjustable rheological properties, modulus, swelling ratios, and degradation rate by control over Zn\n                    <jats:sup>2+<\/jats:sup>\n                    concentration. This unique tactic enables the sustained Cur release, ensuring long\u2010term antioxidant activity and reactive oxygen species (ROS) scavenging. An in vivo experiment in a rat\n                    <jats:italic>S. aureus<\/jats:italic>\n                    \u2010infected wound model demonstrates that the composite hydrogel significantly accelerates wound healing by massacring bacteria, inhibiting inflammation, as well as promoting collagen deposition and angiogenesis. Overall, this effort paves the way for arming Cur, offering a potent antibiotic\u2010free candidate for bacteria\u2010invaded wound management.\n                  <\/jats:p>","DOI":"10.1002\/adhm.202503683","type":"journal-article","created":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T09:50:21Z","timestamp":1762249821000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Multifunctional Ionic Composite Hydrogel with Curcumin Capsule for Promoting Infected Wound Healing"],"prefix":"10.1002","volume":"15","author":[{"given":"Hao\u2010Jie","family":"Tan","sequence":"first","affiliation":[{"name":"College of Polymer Science and Engineering State Key Laboratory of Advanced Polymer Materials  Chengdu 610065 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yan","sequence":"additional","affiliation":[{"name":"College of Polymer Science and Engineering State Key Laboratory of 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