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Current therapeutic modalities, topical, conventional systemic, and biologic, present significant limitations. Topical agents often exhibit inadequate penetration through psoriatic plaques, yielding suboptimal outcomes. Systemic therapies and biologics, while more potent, carry risks of serious adverse effects, necessitating rigorous monitoring and limiting their long\u2010term utility. Despite these challenges, optimizing existing treatment strategies remains valuable. Microneedle technology has emerged as a minimally invasive, skin\u2010targeted approach offering enhanced drug delivery, localization, and patient compliance. This review provides an in\u2010depth analysis of microneedle\u2010based strategies tailored for psoriasis, beginning with current therapy shortcomings, unmet needs in psoriasis management, and principles of microneedle technology. 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