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This constraint restricts impeller size and necessitates ultra\u2010high rotational speeds for adequate blood flow, which in turn increases hemolysis risk. Here we present the on\u2010demand Morphing Flexible Impeller Pump (MFP), which mitigates this trade\u2010off via an integrated deployable linkage system inspired by umbrella opening mechanisms. This system converts simple pushing force into complex spatial deformation of the pump's flexible blades, allowing the MFP to transition from a 7\u00a0mm\u2010diameter catheter\u2010deliverable profile to a 16 mm\u2010diameter helical pumping configuration in situ. The enlarged pumping geometry achieves a clinically relevant pressure gradient of 10 mmHg at 4000 rpm, markedly lower than reported speeds of typical micro\u2010axial pumps. CFD analyses showed that shear stresses were largely below the hemolysis\u2010related threshold (150 Pa), with minimal high\u2010stress volumes. Consistently, in vitro experiments showed hemolysis indices comparable to clinically used pumps (e.g., Impella CP) under matched hemodynamic conditions. By decoupling delivery size from pumping capacity, this morphing\u2010impeller strategy offers a promising route toward safer and more efficient minimally invasive circulatory support.<\/jats:p>","DOI":"10.1002\/adhm.202504792","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T04:54:40Z","timestamp":1773032080000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["An On\u2010demand Morphing Impeller Pump for Low\u2010Speed, Hemocompatible pVADs"],"prefix":"10.1002","volume":"15","author":[{"given":"Xiaolong","family":"Chen","sequence":"first","affiliation":[{"name":"School of Mechanical Engineering Tongji University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyan","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Tongji University  Shanghai 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