{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:54:39Z","timestamp":1781855679968,"version":"3.54.5"},"reference-count":47,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T00:00:00Z","timestamp":1773532800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The challenges of thermoplastic polyurethane (TPU) based ureteral stents are surface lubrication, bacterial adhesion, and Ca\n                    <jats:sup>2+<\/jats:sup>\n                    \/Mg\n                    <jats:sup>2+<\/jats:sup>\n                    ions deposition. In this work, a new amphiphilic copolymer for ureteral stent was reported to avoid the limitations of TPU ureteral stents. Poly(\u03b5\u2010caprolactone) (PCL) and polyethylene glycol (PEG) blocks were reacted with hexamethylene diisocyanate (HDI) to form amphiphilic multiblock copolymers (PCEU). The PCEU was extruded into ureteral stents (PCEU\u2010Stent). The PEG blocks and PCL crystals aligned along the radial direction and resulted in phase\u2010separated microstructures. The subsequent uniaxial stretching of the ureteral stents extended PCL crystals as physical crosslinkers to strengthen axial elasticity. Implantation of the stents in simulated body fluid induced surface migration of PEG, forming a PEG shielding layer around the ureteral stents. This surface reconstruction endowed the ureteral stents with excellent self\u2010lubrication, resistance to bacterial adhesion, and effective inhibition of Ca\n                    <jats:sup>2+<\/jats:sup>\n                    \/Mg\n                    <jats:sup>2+<\/jats:sup>\n                    ions deposition.\n                  <\/jats:p>","DOI":"10.1002\/adhm.202505408","type":"journal-article","created":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T05:20:58Z","timestamp":1773638458000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Water\u2010Driven PEG Shielding of Ureteral Stent for Self\u2010Lubrication and Adhesion Resistance"],"prefix":"10.1002","volume":"15","author":[{"given":"Jing","family":"Li","sequence":"first","affiliation":[{"name":"National Engineering Research Center for Biomaterials College of Biomedical Engineering Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dingke","family":"Liu","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biomaterials College of Biomedical Engineering Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunpeng","family":"Wang","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biomaterials College of Biomedical Engineering Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Ding","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biomaterials College of Biomedical Engineering Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxia","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Pharmacy Chengdu University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology West China Hospital, Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Bai","sequence":"additional","affiliation":[{"name":"Ningbo Baoting Biotechnology LTD  Ningbo China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0939-9869","authenticated-orcid":false,"given":"Bin","family":"He","sequence":"additional","affiliation":[{"name":"National Engineering Research Center for Biomaterials College of Biomedical Engineering Sichuan University  Chengdu China"},{"name":"Tianfu Jincheng Laboratory  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287210370699"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2019.08.16"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/1756287209341306"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2004.10.018"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/17434440.2021.1939010"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202307760"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymdegradstab.2019.06.026"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.11.005"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmt.2016.07.006"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345\u2010017\u20102124\u20103"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.33237"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.34730"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202006815"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.07.025"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2014.06.004"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201501726"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/d1tb00499a"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.0c00481"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.04.072"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202005759"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01088"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.11.029"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202420344"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010021\u201020931\u2010z"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbad019"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbad101"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbae111"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/end.2016.0129"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202310271"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.porgcoat.2024.108512"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202423029"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/c8tb02313a"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/rb\/rbac087"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adi8505"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0032\u20103861(00)00597\u20108"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1039\/d4mh01003e"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1557\/jmr.2013.93"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2023.105668"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2022.112452"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202412083"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202405243"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.08.024"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym14245367"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/pen.25501"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202213294"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00240\u2010011\u20100426\u20102"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2020.125667"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202505408","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/adhm.202505408","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.202505408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T07:43:21Z","timestamp":1781855001000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.202505408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,15]]},"references-count":47,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2026,5]]}},"alternative-id":["10.1002\/adhm.202505408"],"URL":"https:\/\/doi.org\/10.1002\/adhm.202505408","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,15]]},"assertion":[{"value":"2025-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e05408"}}