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Consequently, the development of advanced smart wound\u2010dressing systems, such as bioelectronics\u2010integrated wound dressings, has the potential to address numerous clinical challenges associated with effective wound management. Herein, we introduce a versatile Janus film composed of MXene@PEDOT:PSS and bacterial cellulose (designated as MPP\/BC), developed as an innovative and adaptable bioelectronics\u2010integrated wound dressing. This material is designed to enhance skin bioelectronics for health monitoring while facilitating accelerated wound healing. The resulting MPP\/BC Janus film exhibits remarkable flexibility, high conductivity, photothermal sterilization capabilities, and excellent biocompatibility. These essential characteristics render it suitable for integration into a versatile epidermal sensor capable of real\u2010time monitoring of various human physiological signals. Furthermore, this MPP\/BC Janus film\u2010based wound dressing demonstrates significant potential in enhancing therapeutic efficacy to promote wound healing by facilitating epithelial regeneration and increasing collagen deposition. Consequently, this study introduces a promising strategy for developing advanced smart wound\u2010dressing systems aimed at accelerating and optimizing the wound healing process. This bioelectronics\u2010integrated wound dressing holds significant potential for applications in skin bioelectronics, particularly in continuous health monitoring and intelligent wound management.<\/jats:p>","DOI":"10.1002\/adhm.202505931","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:31:25Z","timestamp":1773757885000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Skin\u2010Inspired MXene@PEDOT:PSS\/Bacterial Cellulose Janus Film for Enhanced Skin Bioelectronics and Accelerated Wound Healing"],"prefix":"10.1002","volume":"15","author":[{"given":"Jingwen","family":"Zhang","sequence":"first","affiliation":[{"name":"Key Laboratory of Applied Surface and Colloid Chemistry, Shaanxi Key Laboratory For Advanced Energy Devices, Shaanxi Engineering Lab For Advanced Energy Technology, National Ministry of Education, School of Materials Science and Engineering Shaanxi Normal 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