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In this work, we report a multifunctional composite hydrogel (CBA) that enables simultaneous teeth whitening and antibacterial activity through the synergistic coupling of localized surface plasmon resonance (LSPR) and piezo\u2010phototropic effects. The CBA hydrogel, comprising BaTiO\n                    <jats:sub>3<\/jats:sub>\n                    nanocubes decorated with Au nanoparticles and embedded in a biocompatible calcium alginate hydrogel matrix, can efficiently generate reactive oxygen species (ROS) under combined light and ultrasound stimulation. This dual activation greatly enhances pigment degradation on enamel surfaces and effectively inactivates pathogenic bacteria such as\n                    <jats:italic>Fusobacterium nucleatum<\/jats:italic>\n                    . Compared with the control group, the hydrogel exhibits three orders of magnitude reduction in bacteria inactivation and a six\u2010fold increase in whitening efficiency, while maintaining excellent enamel integrity. Photoelectrochemical and photoluminescence analyses reveal that the synergistic interaction among the LSPR\u2010induced hot electrons, piezoelectric polarization field, and semiconductor band modulation significantly improves charge separation and ROS generation efficiency. This work not only provides fundamental insights into the cooperative mechanism of LSPR and piezo\u2010phototronic effects but also establishes a practical and safe approach for next\u2010generation dental care materials.\n                  <\/jats:p>","DOI":"10.1002\/adhm.71257","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T04:57:47Z","timestamp":1778734667000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Robust Strategy for Efficient Teeth Whitening and Oral Sterilization Leveraging the Synergistic Coupling of LSPR and Piezo\u2010Phototronic Effects"],"prefix":"10.1002","volume":"15","author":[{"given":"Hang","family":"Yin","sequence":"first","affiliation":[{"name":"State Key Laboratory of Flexible Electronics (LoFE) and Institute of Advanced Materials (IAM) Jiangsu Provincial Industrial Technology Engineering Center for Flexible Mechatronics and Energy Systems Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology Nanjing University of Posts and Telecommunications  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoye","family":"Li","sequence":"additional","affiliation":[{"name":"Research Institute of Stomatology Nanjing Stomatological Hospital Affiliated Hospital of Medical School Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9098-7010","authenticated-orcid":false,"given":"Ao","family":"He","sequence":"additional","affiliation":[{"name":"Research Institute of Stomatology Nanjing Stomatological Hospital Affiliated Hospital of Medical School Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoying","family":"Dai","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics (LoFE) and Institute of Advanced Materials (IAM) Jiangsu 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Key Laboratory of Smart Biomaterials and Theranostic Technology Nanjing University of Posts and Telecommunications  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics (LoFE) and Institute of Advanced Materials (IAM) Jiangsu Provincial Industrial Technology Engineering Center for Flexible Mechatronics and Energy Systems Jiangsu Key Laboratory of Smart Biomaterials and Theranostic Technology Nanjing University of Posts and Telecommunications  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuyi","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Flexible Electronics (LoFE) and Institute of Advanced Materials (IAM) Jiangsu Provincial Industrial Technology Engineering Center for Flexible Mechatronics and Energy Systems Jiangsu Key Laboratory of Smart Biomaterials and Theranostic 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