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Traditional clinical rating scales for disease severity rely on clinician observation and patient self\u2010report, often failing to capture the dynamic and continuous nature of tremors in daily life. This drives the development of objective monitoring technologies, such as wearable sensors, for more accurate evaluation of PD severity. However, many existing systems use rigid materials that lack the mechanical compliance and skin conformability required for stable biointegration. This review summarizes advances in flexible wearable sensors for PD tremor assessment from material innovations to a device engineering perspective, covering inertial measurement units (IMUs), electromyography (EMG), and emerging self\u2010powered systems such as triboelectric (TENG) and piezoelectric nanogenerators (PENG). This review highlightshow functional materials, microstructural design, and device architectures govern sensing mechanisms and performance, with particular emphasis on the transition from rigid components to soft, skin\u2010interfaced technologies. Recent patent activity reflects a shift toward multimodal, wireless, and clinically integrated platforms. Despite progress, challenges remain, including motion artifacts, durability, and limited large\u2010scale clinical validation. Integration of flexible materials, self\u2010powered designs, and AI\u2010driven analytics enables continuous, personalized monitoring, moving closer to real\u2010world clinical deployment and improved patient care.<\/jats:p>","DOI":"10.1002\/adhm.71380","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T09:04:33Z","timestamp":1782464673000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Flexible and Self\u2010Powered Wearable Sensors for Tremor Monitoring in Parkinson'S Disease: Recent Advances in Materials and Device Architectures"],"prefix":"10.1002","volume":"15","author":[{"given":"Sirinya","family":"Ukasi","sequence":"first","affiliation":[{"name":"Department of Chemistry School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"},{"name":"Advanced Materials Research Unit School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sugato","family":"Hajra","sequence":"additional","affiliation":[{"name":"Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1180-7830","authenticated-orcid":false,"given":"Hoe Joon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Robotics and Mechatronics Engineering Daegu Gyeongbuk Institute of Science and Technology  Daegu South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5893-6093","authenticated-orcid":false,"given":"Saichon","family":"Sriphan","sequence":"additional","affiliation":[{"name":"Advanced Materials Research Unit School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"},{"name":"Faculty of Science Energy and Environment King Mongkut's University of Technology North Bangkok  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satana","family":"Pongampai","sequence":"additional","affiliation":[{"name":"Advanced Materials Research Unit School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"},{"name":"Department of Electronics Engineering School of Engineering King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9027-9556","authenticated-orcid":false,"given":"Thitirat","family":"Charoonsuk","sequence":"additional","affiliation":[{"name":"Advanced Materials Research Unit School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"},{"name":"Department of Materials Science Faculty of Science Srinakharinwirot University  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naratip","family":"Vittayakorn","sequence":"additional","affiliation":[{"name":"Department of Chemistry School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"},{"name":"Advanced Materials Research Unit School of Science King Mongkut's Institute of Technology Ladkrabang  Bangkok Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2022.101834"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010022\u201007957\u2010z"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2007.131045"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000011654"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/s20205817"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12984\u2010019\u20100548\u20102"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/s20092605"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/1531\u20108257(199909)14:5<754::AID\u2010MDS1007>3.0.CO;2\u20101"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.2196\/mhealth.3956"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.5334\/tohm.240"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-017-1881-x"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/s20092630"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2020.2978197"},{"key":"e_1_2_12_15_1","doi-asserted-by":"crossref","unstructured":"D.Vera AnayaandM. 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