{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T09:35:53Z","timestamp":1786700153191,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"30","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Acute myocardial infarction (AMI) requires rapid diagnosis beyond conventional methods, which suffer from biological interference and complexity, limiting point\u2010of\u2010care (POC) application. To tackle these issues, we have devised an anthraquinone (AQ)\u2010calibrated sensor unit coupled with smartphone\u2010based analysis for universal detection of AMI biomarkers in untreated whole blood. Our novel dual\u2010channel biosensing platform integrates AQ as an intrinsic reference standard, establishing a self\u2010correction mechanism to effectively counteract hematological matrix influences. The platform enables swift quantification at pg\/mL levels within 5\u00a0min without sample preprocessing, achieving detection limits of 0.3, 19.7, and 0.7\u00a0pg\/mL for cTnI, Mb, and CK\u2011MB, respectively. The smartphone\u2011based intelligent analyzer automates real\u2010time signal processing, creating a closed\u2010loop POC diagnostic setup that shows promise for future at\u2011home AMI risk monitoring. This technological breakthrough showcases notable resilience to biological matrix interference while upholding analytical sensitivity comparable to clinical standards, representing a significant step toward decentralized cardiovascular emergency management.<\/jats:p>","DOI":"10.1002\/adhm.71408","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T11:21:12Z","timestamp":1783077672000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Smartphone\u2010Enabled Point\u2010of\u2010Care Biosensing Platform With Self\u2010Calibration for Rapid Matrix\u2010Resistant Detection of Multiple AMI Biomarkers in Whole Blood"],"prefix":"10.1002","volume":"15","author":[{"given":"Beibei","family":"Lu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Resource Insects College of Sericulture Textile and Biomass Sciences Southwest University  Chongqing China"},{"name":"College of Pharmaceutical Sciences Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaibin","family":"Gong","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Resource Insects College of Sericulture Textile and Biomass Sciences Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Huang","sequence":"additional","affiliation":[{"name":"College of Engineering and Technology Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuaifa","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Cardiology The Sixth People's Hospital of Huizhou  Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Yu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Resource Insects College of Sericulture Textile and Biomass Sciences Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bitao","family":"Lu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Resource Insects College of Sericulture Textile and Biomass Sciences Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangqian","family":"Lan","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Resource Insects College of Sericulture Textile and Biomass Sciences Southwest University  Chongqing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu16132125"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cli11020030"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.26226"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/clc.24261"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.012188"},{"issue":"1","key":"e_1_2_9_7_1","article-title":"Prognostic Value of Initial QRS Analysis in Acute Anterior Myocardial Infarction: Correlation With Left Ventricular Systolic Dysfunction, Serum Biomarkers, and Cardiac Outcomes","volume":"26","author":"Castillo M. 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