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These pathological conditions highlight the need for advanced biomaterial platforms capable of actively modulating cell behavior through biochemical, mechanical, and electrical cues relevant to the skin microenvironment. In this study, a multicomponent electrically conductive hydrogel scaffold composed of the self\u2010assembling dipeptide Fluorenylmethoxycarbonyl diphenylalanine (FmocFF), Ti\n                    <jats:sub>3<\/jats:sub>\n                    C\n                    <jats:sub>2<\/jats:sub>\n                    T\n                    <jats:sub>x<\/jats:sub>\n                    MXene nanosheets, and hyaluronic acid (HA) is presented. The FmocFF\/MXene\/HA hydrogel integrates structural, electrical, and biochemical functionalities together with a self\u2010healing capability within a single platform, providing an extracellular matrix\u2010like fibrous architecture, stable electrical conductivity for controlled stimulation, and HA\u2010mediated bioactivity to support cellular responses. The MXene nanosheets enhanced the mechanical stiffness of the hydrogel, and formed percolated conductive pathways, while the peptide matrix protected MXene from oxidation. In vitro studies confirmed excellent cytocompatibility and cell attachment. Importantly, electrical stimulation at physiologically relevant voltages, consistent with the endogenous transepithelial potential of the skin, significantly enhanced fibroblast proliferation and accelerated migration across cell\u2010free regions, demonstrating the scaffold's ability to support electrically stimulated cell activity. These findings establish the FmocFF\/MXene\/HA composite hydrogel as a promising platform for electrically assisted tissue regeneration.\n                  <\/jats:p>","DOI":"10.1002\/adhm.71487","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T05:01:56Z","timestamp":1785992516000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Multicomponent Peptide\u2010MXene\u2010Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3884-8937","authenticated-orcid":false,"given":"Offir","family":"Loboda","sequence":"first","affiliation":[{"name":"Department of Oral Biology The Goldschleger School of Dental Medicine The Gray Faculty of Medical &amp; Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Jan Koum Center For Nanoscience and Nanotechnology Tel Aviv University  Tel Aviv Israel"},{"name":"The Center for Physics &amp; Chemistry of Living Systems Tel Aviv University  Tel Aviv Israel"},{"name":"Sagol Center for Regenerative Biotechnology Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4172-8511","authenticated-orcid":false,"given":"Dana","family":"Cohen\u2010Gerassi","sequence":"additional","affiliation":[{"name":"Department of Oral Biology The Goldschleger School of Dental Medicine The Gray Faculty of Medical &amp; Health Sciences Tel Aviv University  Tel Aviv Israel"},{"name":"Jan Koum Center For Nanoscience and Nanotechnology Tel Aviv University  Tel Aviv Israel"},{"name":"The Center for Physics &amp; Chemistry of Living Systems Tel Aviv University  Tel Aviv Israel"},{"name":"Sagol Center for Regenerative Biotechnology Tel Aviv University  Tel Aviv Israel"},{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dor Aaron","family":"Goldstein","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Or","family":"Messer","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bar","family":"Favelukis","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ehud","family":"Gazit","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering Tel Aviv University  Tel Aviv Israel"},{"name":"The Shmunis School of Biomedicine and Cancer Research George S. 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