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Here, we report a large language model (LLM)\u2010driven throat\u2010wearable sensing system (TWSS) for real\u2010time monitoring of laryngeal activity and quantitative assessment of swallowing function. TWSS consists of a flexible sensing patch and a structured signal sequence\u2013based LLM framework (S3\u2010LLM). The flexible patch integrates a stretchable sensor with a wireless circuit module, enabling conformal attachment to the throat and real\u2010time acquisition of physiological signals. Owing to its dual sensitivity to pressure and strain, the sensor can capture subtle and complex laryngeal movements associated with different physiological activities. S3\u2010LLM converts them into structured signal sequences and combines temporal encoding with parameter\u2010efficient fine\u2010tuning, thereby exploiting the representation and generalization capabilities of LLMs under few\u2010shot conditions. In a clinical validation involving 20 participants, TWSS achieved an accuracy of 92.4% for recognizing normal laryngeal activities and 87.6% for evaluating swallowing function, approximately 20% improvement over conventional models. These results demonstrate that TWSS provides a promising wearable platform for continuous, objective, and quantitative assessment of swallowing disorders and highlights the potential for personalized healthcare.<\/jats:p>","DOI":"10.1002\/adhm.71548","type":"journal-article","created":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T05:06:48Z","timestamp":1785992808000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Large Language Model\u2010Driven Throat\u2010Wearable Sensing System for Real\u2010Time Recognition and Evaluation of Swallowing Disorders"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-6834-0222","authenticated-orcid":false,"given":"Zitang","family":"Yuan","sequence":"first","affiliation":[{"name":"School of Instrumentation and Optoelectronic Engineering Beihang University  Beijing 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