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However, GI anatomy, function, and motility disorders are primarily examined by radiographic imaging, which exposes patients to ionizing radiation and yields only coarse proxies of how a meal moves through the gut. By contrast, fluorine\u201019 (\n                    <jats:sup>19<\/jats:sup>\n                    F) MRI offers background\u2010free, quantitative tracking, but most oral\n                    <jats:sup>19<\/jats:sup>\n                    F agents are hydrophobic and phase\u2010separate from chyme, generating layering artifacts, which spoil motility and anatomy readouts. Here, we developed nonresorbable, hydrophilic fluorinated polymer tracers miscible with luminal contents. These tracers provided a strong, quantifiable\n                    <jats:sup>19<\/jats:sup>\n                    F signal for combined\n                    <jats:sup>1<\/jats:sup>\n                    H\/\n                    <jats:sup>19<\/jats:sup>\n                    F MRI and\n                    <jats:sup>19<\/jats:sup>\n                    F spectroscopy, enabling us to visualize GI anatomy and transit noninvasively. In vivo imaging reliably tracked whole\u2010gut transit and fecal elimination, with no evidence of systemic uptake or tissue injury. As such, this practical, reproducible, and radiation\u2010free platform for phenotyping dysmotility and monitoring therapeutic response may open up opportunities for longitudinal GI studies and clinical trials.\n                  <\/jats:p>","DOI":"10.1002\/adhm.71667","type":"journal-article","created":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T04:53:14Z","timestamp":1789361594000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Hydrophilic Polymers Enable Gastrointestinal Transit Monitoring by Fluorine\u201019 Magnetic Resonance Imaging"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3164-6168","authenticated-orcid":false,"given":"Ond\u0159ej","family":"Groborz","sequence":"first","affiliation":[{"name":"Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences  Prague Czech Republic"},{"name":"Institute of Biophysics and Informatics First Faculty of 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