{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T12:34:15Z","timestamp":1793104455868,"version":"4.5.0"},"reference-count":123,"publisher":"Wiley","issue":"40","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS\u20102024\u201000338853"],"award-info":[{"award-number":["RS\u20102024\u201000338853"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022R1A5A8023404"],"award-info":[{"award-number":["2022R1A5A8023404"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002644","name":"Pukyong National University","doi-asserted-by":"publisher","award":["202506850001"],"award-info":[{"award-number":["202506850001"]}],"id":[{"id":"10.13039\/501100002644","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Adv Healthcare Materials"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The development of CRISPR\u2010Cas9 technology has transformed gene editing with precise mutations in DNA targeted to treat genetic disorders yet various challenges such as immunogenicity, off\u2010target editing, and lack of temporal control after delivery, making it difficult for therapeutic agents to reach deep tissues like brain, and cardiac tissues. Ultrasound has emerged as a promising solution by influencing sonogenetic modulation and delivery of CRISPR tools in deep tissues for targeted gene editing. Sonogenetic editing has revolutionized the technological advancement of CRISPR\u2010editing and among multiple strategies, ultrasound\u2010mediated delivery of CRISPR systems has enabled non\u2010invasive and controlled genome editing through sonoporation, and upregulation of stimuli\u2010responsive genes. Focused ultrasound combined with microbubbles has demonstrated CRISPR delivery to brain tissue with \u223c80% higher efficiency than traditional strategies, allowing precise and advanced treatment of neurodegenerative diseases. In cancer applications, ultrasound has enabled complete tumor eradication via sonodynamic therapy, achieving 64% tumor regression via CAR T\u2010cell therapy. Significant advances in gene therapy for cardiovascular diseases, obesity, and related diseases were also demonstrated recently. Collectively, the review elaborates potential of ultrasound\u2010CRISPR technologies as a powerful tool that enables targeted, and image\u2010guided genetic interventions, capable of advancing the outcomes of gene therapy as a widespread clinical practice.<\/jats:p>","DOI":"10.1002\/adhm.71753","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:26:47Z","timestamp":1790396807000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Ultrasound\u2010Mediated CRISPR Delivery and Sonogenetic Modulation for Precision Therapeutics"],"prefix":"10.1002","volume":"15","author":[{"given":"Sara","family":"Maham","sequence":"first","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0026-6402","authenticated-orcid":false,"given":"Badrinathan","family":"Sridharan","sequence":"additional","affiliation":[{"name":"Department of Biotechnology School of Sciences and Humanities SR University  Warangal Telangana India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Hyeong","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Pukyong National University  Busan Republic of Korea"},{"name":"Department of Industry 4.0 Convergence Bionics Engineering Pukyong National University  Busan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4450-8236","authenticated-orcid":false,"given":"ChoEun","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeong Seo","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1467-8807","authenticated-orcid":false,"given":"Daehun","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeongho","family":"Sung","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Pukyong National University  Busan Republic of Korea"},{"name":"Department of Industry 4.0 Convergence Bionics Engineering Pukyong National University  Busan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taeyang","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering Pukyong National University  Busan Republic of Korea"},{"name":"Department of Industry 4.0 Convergence Bionics Engineering Pukyong National University  Busan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7008-1227","authenticated-orcid":false,"given":"Juhyun","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4182-7130","authenticated-orcid":false,"given":"Hae Gyun","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Electronics Engineering Hanyang University  Seoul Republic of Korea"},{"name":"Department of Biomedical Engineering Pukyong National University  Busan Republic of Korea"},{"name":"Department of Biomedical Engineering Hanyang University  Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"e_1_2_19_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059\u2010025\u201003667\u20107"},{"key":"e_1_2_19_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2021.673286"},{"key":"e_1_2_19_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.973326"},{"key":"e_1_2_19_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010021\u201000645\u2010w"},{"key":"e_1_2_19_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nwnano.2024.100032"},{"key":"e_1_2_19_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/asia.202300090"},{"key":"e_1_2_19_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000549834"},{"key":"e_1_2_19_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2025.07.009"},{"key":"e_1_2_19_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2023.109051"},{"key":"e_1_2_19_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adf4888"},{"key":"e_1_2_19_12_1","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.14140245"},{"key":"e_1_2_19_13_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.28717"},{"key":"e_1_2_19_14_1","volume-title":"Power Ultrasonics: Applications of High\u2010Intensity Ultrasound","author":"Gallego\u2010Ju\u00e1rez J. A.","year":"2023"},{"key":"e_1_2_19_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2BM01636B"},{"key":"e_1_2_19_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010021\u201000645\u2010w"},{"key":"e_1_2_19_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.1c01143"},{"key":"e_1_2_19_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104\u2010023\u201006298\u2010y"},{"key":"e_1_2_19_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.01.042"},{"key":"e_1_2_19_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2019.02.027"},{"key":"e_1_2_19_21_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43141\u2010020\u201000078\u2010y"},{"key":"e_1_2_19_22_1","doi-asserted-by":"publisher","DOI":"10.1109\/OJEMB.2022.3192103"},{"key":"e_1_2_19_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201031365\u20106"},{"key":"e_1_2_19_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2024.103694"},{"key":"e_1_2_19_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20101\u20100716\u20102301\u20105_2"},{"key":"e_1_2_19_26_1","doi-asserted-by":"publisher","DOI":"10.1094\/PHYTO\u201010\u201022\u20100365\u2010KD"},{"key":"e_1_2_19_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40694\u2010024\u201000180\u20107"},{"key":"e_1_2_19_28_1","doi-asserted-by":"publisher","DOI":"10.1177\/0023677221994613"},{"key":"e_1_2_19_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581\u2010022\u201000636\u20102"},{"key":"e_1_2_19_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.124054"},{"key":"e_1_2_19_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.add8643"},{"key":"e_1_2_19_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568\u2010022\u201000441\u2010w"},{"key":"e_1_2_19_33_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abi9335"},{"key":"e_1_2_19_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/biot.202100507"},{"key":"e_1_2_19_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00106"},{"key":"e_1_2_19_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2025.01.013"},{"key":"e_1_2_19_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2005.01.011"},{"key":"e_1_2_19_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2302910120"},{"key":"e_1_2_19_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.05.017"},{"key":"e_1_2_19_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201048974\u2010y"},{"key":"e_1_2_19_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201054477\u20107"},{"key":"e_1_2_19_42_1","doi-asserted-by":"publisher","DOI":"10.34133\/2022\/976450"},{"key":"e_1_2_19_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201045273\u20104"},{"key":"e_1_2_19_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.146322"},{"key":"e_1_2_19_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/pr11082432"},{"key":"e_1_2_19_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2025.107533"},{"key":"e_1_2_19_47_1","doi-asserted-by":"publisher","DOI":"10.34133\/adi.0083"},{"key":"e_1_2_19_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/s23073608"},{"key":"e_1_2_19_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/admt.202100798"},{"key":"e_1_2_19_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416\u2010022\u201002076\u2010y"},{"key":"e_1_2_19_51_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S504363"},{"key":"e_1_2_19_52_1","doi-asserted-by":"publisher","DOI":"10.1109\/TUFFC.2023.3261420"},{"key":"e_1_2_19_53_1","doi-asserted-by":"publisher","DOI":"10.55544\/jrasb.3.4.4"},{"key":"e_1_2_19_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202505154"},{"key":"e_1_2_19_55_1","doi-asserted-by":"publisher","DOI":"10.1145\/3447243"},{"key":"e_1_2_19_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010021\u201002833\u20109"},{"key":"e_1_2_19_57_1","doi-asserted-by":"publisher","DOI":"10.1177\/11297298211018060"},{"key":"e_1_2_19_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/978\u20103\u2010031\u201085308\u20101_10"},{"key":"e_1_2_19_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12880\u2010022\u201000839\u2010w"},{"key":"e_1_2_19_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crmeth.2025.100983"},{"key":"e_1_2_19_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcam.2025.101010"},{"key":"e_1_2_19_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276\u2010025\u201001463\u20108"},{"key":"e_1_2_19_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.75563"},{"key":"e_1_2_19_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010019\u201039090\u20109"},{"key":"e_1_2_19_65_1","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2023.1339189"},{"key":"e_1_2_19_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119736"},{"key":"e_1_2_19_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13346\u2010025\u201001828\u20106"},{"key":"e_1_2_19_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2007.08.004"},{"key":"e_1_2_19_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201028205\u2010y"},{"key":"e_1_2_19_70_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.1c00886"},{"key":"e_1_2_19_71_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202317112"},{"key":"e_1_2_19_72_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2300291120"},{"key":"e_1_2_19_73_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.39786"},{"key":"e_1_2_19_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010025\u201002387\u20105"},{"key":"e_1_2_19_75_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1714900115"},{"key":"e_1_2_19_76_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.119770"},{"key":"e_1_2_19_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201042249\u20108"},{"key":"e_1_2_19_78_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S507322"},{"key":"e_1_2_19_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/anbr.202500176"},{"key":"e_1_2_19_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010018\u201022056\u20108"},{"key":"e_1_2_19_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultras.2023.107238"},{"key":"e_1_2_19_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202005644"},{"key":"e_1_2_19_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.115178"},{"key":"e_1_2_19_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2012.05.017"},{"key":"e_1_2_19_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.11.074"},{"key":"e_1_2_19_86_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ads4711"},{"key":"e_1_2_19_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202101946"},{"key":"e_1_2_19_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41593\u2010020\u201000778\u20101"},{"key":"e_1_2_19_89_1","doi-asserted-by":"publisher","DOI":"10.20517\/cdr.2023.82"},{"key":"e_1_2_19_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2023.12.005"},{"key":"e_1_2_19_91_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c05270"},{"key":"e_1_2_19_92_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41434\u2010025\u201000517\u2010w"},{"key":"e_1_2_19_93_1","doi-asserted-by":"publisher","DOI":"10.14218\/GE.2024.00002"},{"key":"e_1_2_19_94_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41434\u2010023\u201000421\u20101"},{"key":"e_1_2_19_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.16541"},{"key":"e_1_2_19_96_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232214188"},{"key":"e_1_2_19_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-13-9636-6_2"},{"key":"e_1_2_19_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481\u2010019\u201009849\u2010y"},{"key":"e_1_2_19_99_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.695808"},{"key":"e_1_2_19_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010022\u201035580\u2010z"},{"key":"e_1_2_19_101_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201708689"},{"key":"e_1_2_19_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202104641"},{"key":"e_1_2_19_103_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2024.2410619"},{"key":"e_1_2_19_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-34199-1.00003-X"},{"key":"e_1_2_19_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/jum.16096"},{"key":"e_1_2_19_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.20179"},{"key":"e_1_2_19_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060\u2010021\u201003887\u20104"},{"key":"e_1_2_19_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571\u2010018\u20100003\u20105"},{"key":"e_1_2_19_109_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.124.070535"},{"key":"e_1_2_19_110_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001077"},{"key":"e_1_2_19_111_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010025\u201089823\u20102"},{"key":"e_1_2_19_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2021.09.005"},{"key":"e_1_2_19_113_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics16030343"},{"key":"e_1_2_19_114_1","doi-asserted-by":"publisher","DOI":"10.1097\/RLI.0000000000001116"},{"key":"e_1_2_19_115_1","doi-asserted-by":"publisher","DOI":"10.1111\/obr.13978"},{"key":"e_1_2_19_116_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.02.004"},{"key":"e_1_2_19_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201056755\u20104"},{"key":"e_1_2_19_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392\u2010023\u201001309\u20107"},{"key":"e_1_2_19_119_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2019.1567490"},{"key":"e_1_2_19_120_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.8b03779"},{"key":"e_1_2_19_121_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.4306"},{"key":"e_1_2_19_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2011.34"},{"key":"e_1_2_19_123_1","doi-asserted-by":"publisher","DOI":"10.1080\/17458080801993422"},{"key":"e_1_2_19_124_1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.70464"}],"container-title":["Advanced Healthcare Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.71753","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/adhm.71753","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adhm.71753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T11:52:00Z","timestamp":1793101920000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adhm.71753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":123,"journal-issue":{"issue":"40","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/adhm.71753"],"URL":"https:\/\/doi.org\/10.1002\/adhm.71753","archive":["Portico"],"relation":{},"ISSN":["2192-2640","2192-2659"],"issn-type":[{"value":"2192-2640","type":"print"},{"value":"2192-2659","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"assertion":[{"value":"2026-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e71753"}}