{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:45Z","timestamp":1791244845060,"version":"4.1.0"},"reference-count":66,"publisher":"Wiley","issue":"45","license":[{"start":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T00:00:00Z","timestamp":1503446400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21273017"],"award-info":[{"award-number":["21273017"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51103004"],"award-info":[{"award-number":["51103004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004602","name":"Program for New Century Excellent Talents in University","doi-asserted-by":"publisher","award":["NCET\u201012\u20100034"],"award-info":[{"award-number":["NCET\u201012\u20100034"]}],"id":[{"id":"10.13039\/501100004602","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004806","name":"Fok Ying Tong Education Foundation","doi-asserted-by":"publisher","award":["141045"],"award-info":[{"award-number":["141045"]}],"id":[{"id":"10.13039\/501100004806","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004750","name":"Aeronautical Science Foundation of China","doi-asserted-by":"publisher","award":["20145251035"],"award-info":[{"award-number":["20145251035"]}],"id":[{"id":"10.13039\/501100004750","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004750","name":"Aeronautical Science Foundation of China","doi-asserted-by":"publisher","award":["2015ZF21009"],"award-info":[{"award-number":["2015ZF21009"]}],"id":[{"id":"10.13039\/501100004750","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advanced Materials"],"published-print":{"date-parts":[[2017,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Nature is very successful in designing strong and tough, lightweight materials. Examples include seashells, bone, teeth, fish scales, wood, bamboo, silk, and many others. A distinctive feature of all these materials is that their properties are far superior to those of their constituent phases. Many of these natural materials are lamellar or layered in nature. With its \u201cbrick and mortar\u201d structure, nacre is an example of a layered material that exhibits extraordinary physical properties. Finding inspiration in living organisms to create bioinspired materials is the subject of intensive research. Several processing techniques have been proposed to design materials mimicking natural materials, such as layer\u2010by\u2010layer deposition, self\u2010assembly, electrophoretic deposition, hydrogel casting, doctor blading, and many others. Freeze casting, also known as ice\u2010templating, is a technique that has received considerable attention in recent years to produce bioinspired bulk materials. Here, recent advances in the freeze\u2010casting technique are reviewed for fabricating lamellar scaffolds by assembling different dimensional building blocks, including nanoparticles, polymer chains, nanofibers, and nanosheets. These lamellar scaffolds are often infiltrated by a second phase, typically a soft polymer matrix, a hard ceramic matrix, or a metal matrix. The unique architecture of the resultant bioinspired structural materials displays excellent mechanical properties. The challenges of the current research in using the freeze\u2010casting technique to create materials large enough to be useful are also discussed, and the technique's promise for fabricating high\u2010performance nacre\u2010inspired structural materials in the future is reviewed.<\/jats:p>","DOI":"10.1002\/adma.201703155","type":"journal-article","created":{"date-parts":[[2017,8,23]],"date-time":"2017-08-23T03:02:37Z","timestamp":1503457357000},"source":"Crossref","is-referenced-by-count":239,"title":["Freeze Casting for Assembling Bioinspired Structural Materials"],"prefix":"10.1002","volume":"29","author":[{"given":"Qunfeng","family":"Cheng","sequence":"first","affiliation":[{"name":"Key Laboratory of Bio\u2010inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry Beijing Advanced Innovation Center for Biomedical Engineering Beihang University  Beijing 100191 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanjin","family":"Huang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Bio\u2010inspired Smart Interfacial Science and Technology of Ministry of Education School of Chemistry Beijing Advanced Innovation Center for Biomedical Engineering Beihang University  Beijing 100191 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6275-165X","authenticated-orcid":false,"given":"Antoni P.","family":"Tomsia","sequence":"additional","affiliation":[{"name":"Beijing Advanced Innovation Center for Biomedical Engineering Beihang University  Beijing 100191 P. R. China"},{"name":"Materials Sciences Division Lawrence Berkeley National Laboratory  Berkeley CA 94720 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,8,23]]},"reference":[{"key":"e_1_2_6_1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4089"},{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmatsci.2007.05.002"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2016.7"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar400279t"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2016.11.002"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1143176"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat906"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201210166"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200906920"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201004748"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn503755c"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp3064917"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201501983"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201403322"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201503045"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl1003224"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201001577"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4419"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1088\/1748-3182\/7\/3\/031001"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspa.1926.0093"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspa.1926.0092"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1120937"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164865"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/adem.200700270"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/ma3031913"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201301121"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsta.2010.0014"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1557\/jmr.2013.105"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2006.06.028"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actamat.2006.11.003"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1088\/1748-6041\/3\/2\/025005"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.31051"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.b.30997"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1551-2916.2005.00785.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1551-2916.2006.01311.x"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2008.11.009"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-577X(02)01002-9"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1551-2916.2009.03087.x"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1551-2916.2008.02673.x"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1551-2916.2006.01094.x"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2571"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-0248(85)90217-9"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jeurceramsoc.2010.12.021"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.03.031"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008913609857"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.1500849"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat1487"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201501653"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14425"},{"key":"e_1_2_6_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2251"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2008.04.006"},{"key":"e_1_2_6_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat3915"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmps.2012.03.002"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.3499294"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201504051"},{"key":"e_1_2_6_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201603143"},{"key":"e_1_2_6_57_1","volume":"7","author":"Knoller A.","year":"2017","journal-title":"Sci. Rep."},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201200230"},{"key":"e_1_2_6_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b05808"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.32579"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf8991"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2012.10.013"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201506157"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4410"},{"key":"e_1_2_6_65_1","first-page":"E39","volume":"92","author":"Behr S.","year":"2015","journal-title":"Process Eng."},{"key":"e_1_2_6_66_1","unstructured":"\u201cStubborn GE Scientist Creates New Fuel\u2010Saving Material Jonathan Fahey\u201d The Associated Press http:\/\/www.dailynews.com\/science\/20150514\/StubbornGE Scientist Creates New Fuel\u2010Saving Material (accessed: May 2015)."}],"container-title":["Advanced Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fadma.201703155","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adma.201703155","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T10:33:47Z","timestamp":1759746827000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adma.201703155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,23]]},"references-count":66,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2017,12]]}},"alternative-id":["10.1002\/adma.201703155"],"URL":"https:\/\/doi.org\/10.1002\/adma.201703155","archive":["Portico"],"relation":{},"ISSN":["0935-9648","1521-4095"],"issn-type":[{"value":"0935-9648","type":"print"},{"value":"1521-4095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,23]]},"article-number":"1703155"}}