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The strategy of macropore\u2010forming, especially bioactive macropores, holds considerable promise to circumvent this problem, thereby promoting fracture healing. Herein, a class of bioactive glass\u2010involved macropore\u2010embedded bone adhesives is developed, which is capable of facilitating the migration of bone\u2010derived mesenchymal stromal cells into the adhesive layer and differentiation into osteocytes. The integration of bioactive glass\u2010particle\u2010encapsulated porogens in the bone adhesives is key to this approach. A robust instant bonding on the bone adhesive and a high efficiency of bone regeneration on a mouse skull are observed, both of which are vital for clinical applications and personalized surgical procedures. This work represents a general strategy to design biomaterials with high cell\u2010ingrowth efficacy.<\/jats:p>","DOI":"10.1002\/adma.201907491","type":"journal-article","created":{"date-parts":[[2020,1,27]],"date-time":"2020-01-27T03:52:47Z","timestamp":1580097167000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["Bioactive Pore\u2010Forming Bone Adhesives Facilitating Cell Ingrowth for Fracture Healing"],"prefix":"10.1002","volume":"32","author":[{"given":"Liju","family":"Xu","sequence":"first","affiliation":[{"name":"Beijing National Laboratory for Molecular Sciences State Key Laboratory of Polymer Physics and Chemistry CAS Research\/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences  Beijing 100190 China"},{"name":"School of Chemical Sciences University of Chinese Academy of Sciences  Beijing 100190 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