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Here, a soft and absorbable temporary epicardial pacing wire (saTPW) for effectively correcting abnormal heart rates in a rabbit model, such as bradycardia and ventricular premature beat, is developed. The saTPW exhibits excellent conductivity, flexibility, cycling stability (&gt;100\u00a0000 cycles), and less inflammatory response during two\u2010month subcutaneous implantation in a rat model. The saTPW which consists of poly(<jats:sc>l<\/jats:sc>\u2010lactide\u2010<jats:italic>co<\/jats:italic>\u2010\u03b5\u2010caprolactone) and liquid metal, can degrade about 13% (mass loss) in the rats over a two\u2010month subcutaneous implantation. It can be absorbed over time in the body. The cytocompatibility and absorbability avoid secondary injuries caused by remaining wires which are permanently left in the body. The saTPW will provide a great platform for diagnosis and treatments in cardiovascular diseases by delivering the physiological signal and applying electrical stimulation for therapy.<\/jats:p>","DOI":"10.1002\/adma.202101447","type":"journal-article","created":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T06:42:17Z","timestamp":1627108937000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":52,"title":["A Soft and Absorbable Temporary Epicardial Pacing Wire"],"prefix":"10.1002","volume":"33","author":[{"given":"Chen","family":"Hang","sequence":"first","affiliation":[{"name":"Shenzhen Key Laboratory of Smart Healthcare Engineering Department of Biomedical Engineering Southern University of Science and Technology  No. 1088, Xueyuan Rd., Xili, Nanshan District Shenzhen Guangdong 518055 P. R. 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