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Here, a label\u2010free, chemo\u2010resistive\/SERS multimodal sensor based on a systematically assembled 3D cross\u2010point multifunctional nanoarchitecture (3D\u2010CMA), which has unusually strong enhancements in both \u201cchemo\u2010resistive\u201d and \u201cSERS\u201d sensing characteristics is introduced. 3D\u2010CMA combines several sensing mechanisms and sensing elements via 3D integration of semiconducting SnO\n                    <jats:sub>2<\/jats:sub>\n                    nanowire frameworks and dual\u2010functioning Au metallic nanoparticles. It is shown that the multimodal sensor can successfully estimate mixed\u2010gas compositions selectively and quantitatively at the sub\u2010100 ppm level, even for mixtures of gaseous aromatic compounds (nitrobenzene and toluene) with very similar molecular structures. This is enabled by combined chemo\u2010resistive and SERS multimodal sensing providing complementary information.\n                  <\/jats:p>","DOI":"10.1002\/adma.202105199","type":"journal-article","created":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T18:57:28Z","timestamp":1632769048000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Synergistic Integration of Chemo\u2010Resistive and SERS Sensing for Label\u2010Free Multiplex Gas Detection"],"prefix":"10.1002","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7721-9065","authenticated-orcid":false,"given":"Hyeuk Jin","family":"Han","sequence":"first","affiliation":[{"name":"Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology (KAIST)  291 Daehak\u2010ro, Yuseong\u2010gu Daejeon 34141 Republic of Korea"},{"name":"Department of Mechanical Engineering and Materials Science Yale University  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