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While the nacre\u2010mimetic structures are widely adopted in artificial ceramics, the extrinsic mechanisms are often weakened by the relatively low tensile strength of the platelets with a large aspect ratio, which makes the fracture toughness of these materials much lower than expected. Here, it is demonstrated that the fracture toughness of artificial nacre materials with high inorganic contents can be improved by residual stress\u2010induced platelet strengthening, which can catalyze more effective extrinsic toughening mechanisms that are specific to the nacre\u2010mimetic structures. Thereby, while the absolute fracture toughness of the materials is not comparable with advanced ceramic\u2010based composites, the toughness amplification factor of the material reaches 16.1\u00a0\u00b1 1.1, outperforming the state\u2010of\u2010the\u2010art biomimetic ceramics. The results reveal that, with the merit of nacre\u2010mimetic structural designs, the overall fracture toughness of the artificial nacre can be improved by the platelet strengthening through extrinsic toughening mechanisms, although the intrinsic fracture toughness may decrease at platelet level due to the strengthening. It is anticipated that advanced structural ceramics with exceeding performance can be fabricated through these unconventional strategies.<\/jats:p>","DOI":"10.1002\/adma.202108267","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T02:19:49Z","timestamp":1640571589000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":92,"title":["Artificial Nacre with High Toughness Amplification Factor: Residual Stress\u2010Engineering Sparks Enhanced Extrinsic Toughening Mechanisms"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3871-9753","authenticated-orcid":false,"given":"Yu\u2010Feng","family":"Meng","sequence":"first","affiliation":[{"name":"Division of Nanomaterials and Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale Institute of Energy, Hefei Comprehensive National Science Center CAS Center for Excellence in Nanoscience Department of Chemistry Institute of Biomimetic Materials and Chemistry Anhui Engineering Laboratory of Biomimetic Materials University of Science and Technology of China  Hefei 230026 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin\u2010Bo","family":"Zhu","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics CAS Center for Excellence in Complex System Mechanics University of Science and Technology of China  Hefei 230027 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li\u2010Chuan","family":"Zhou","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics CAS Center for Excellence in Complex System Mechanics University of Science and Technology of China  Hefei 230027 China"},{"name":"School of Mechanical Engineering Hefei University of Technology  Hefei 230009 P. 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Laboratory of Biomimetic Materials University of Science and Technology of China  Hefei 230026 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Zhao","sequence":"additional","affiliation":[{"name":"Division of Nanomaterials and Chemistry, Hefei National Laboratory for Physical Sciences at the Microscale Institute of Energy, Hefei Comprehensive National Science Center CAS Center for Excellence in Nanoscience Department of Chemistry Institute of Biomimetic Materials and Chemistry Anhui Engineering Laboratory of Biomimetic Materials University of Science and Technology of China  Hefei 230026 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Xia","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Mechanical Behavior and Design of Materials Department of Modern Mechanics CAS Center for Excellence in Complex System Mechanics University of Science and Technology of China  Hefei 230027 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