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The crosslinks make the hydrogel swell\u2010resistant but brittle. This conflict is resolved here by making a hydrogel from a dough. The dough is formed by mixing long polymer chains with a small amount of water and photoinitiator. The dough is then homogenized by kneading and annealing at elevated temperatures, during which the crowded polymer chains densely entangle. The polymer chains are then sparsely crosslinked into a polymer network under an ultraviolet lamp, and submerged in water to swell to equilibrium. The resulting hydrogel is both swell\u2010resistant and tough. The hydrogel also has near\u2010perfect elasticity, high strength, high fatigue resistance, and low friction. The method is demonstrated with two widely used polymers, poly(ethylene glycol) and cellulose. These hydrogels have never been made swell\u2010resistant, elastic, and tough before. The method is generally applicable to synthetic and natural polymers, and is compatible with industrial processing technologies, opening doors to the development of sustainable, high\u2010performance hydrogels.<\/jats:p>","DOI":"10.1002\/adma.202206577","type":"journal-article","created":{"date-parts":[[2022,9,20]],"date-time":"2022-09-20T13:40:08Z","timestamp":1663681208000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":270,"title":["Making Highly Elastic and Tough Hydrogels from Doughs"],"prefix":"10.1002","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7005-634X","authenticated-orcid":false,"given":"Guodong","family":"Nian","sequence":"first","affiliation":[{"name":"John A. 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