{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T11:39:00Z","timestamp":1792150740052,"version":"4.4.0"},"reference-count":71,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52173079"],"award-info":[{"award-number":["52173079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008387","name":"Xi'an Science and Technology Bureau","doi-asserted-by":"publisher","award":["201805056ZD7CG40"],"award-info":[{"award-number":["201805056ZD7CG40"]}],"id":[{"id":"10.13039\/501100008387","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The elastomers with the combination of high strength and high toughness have always been intensively pursued due to their diverse applications. Biomedical applications frequently require elastomers with biodegradability and biocompatibility properties. It remains a great challenge to prepare the biodegradable elastomers with extremely robust mechanical properties for in vivo use. In this report,\u00a0we\u00a0present a polyurethane elastomer with unprecedented mechanical properties for the in vivo application as hernia patches, which\u00a0was\u00a0obtained by the solvent\u2010free reaction of polycaprolactone (PCL) and isophorone diisocyanate (IPDI) with\n                    <jats:italic>N<\/jats:italic>\n                    ,\n                    <jats:italic>N<\/jats:italic>\n                    \u2010bis(2\u2010hydroxyethyl)oxamide (BHO) as the chain extender. Abundant and hierarchical hydrogen\u2010bonding interactions inside the elastomers hinder the crystallization of PCL segments and facilitate the formation of uniformly distributed hard phase microdomains, which miraculously realize the extremely high strength and toughness with the fracture strength of 92.2\u00a0MPa and true stress of 1.9\u00a0GPa, while maintaining the elongation\u2010at\u2010break of \u22481900% and ultrahigh toughness of 480.2\u00a0MJ m\n                    <jats:sup>\u22123<\/jats:sup>\n                    with the unprecedented fracture energy of 322.2\u00a0kJ m\n                    <jats:sup>\u22122<\/jats:sup>\n                    . Hernia patches made from the elastomer via 3D printing technology exhibit outstanding mechanical properties, biocompatibility, and biodegradability. The robust and biodegradable elastomers demonstrate considerable potentials for in vivo applications.\n                  <\/jats:p>","DOI":"10.1002\/adma.202212130","type":"journal-article","created":{"date-parts":[[2023,2,23]],"date-time":"2023-02-23T18:54:25Z","timestamp":1677178465000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":374,"title":["Extremely Strong and Tough Biodegradable Poly(urethane) Elastomers with Unprecedented Crack Tolerance via Hierarchical Hydrogen\u2010Bonding Interactions"],"prefix":"10.1002","volume":"35","author":[{"given":"Rui","family":"Guo","sequence":"first","affiliation":[{"name":"Engineering Research Center of Energy Storage Materials and Devices Ministry of Education School of Chemistry Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Energy Storage Materials and Devices Ministry of Education School of Chemistry Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youshen","family":"Wu","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Energy Storage Materials and Devices Ministry of Education School of Chemistry Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbing","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanghe","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory for Non\u2010equilibrium Synthesis and Modulation of Condensed Matter School of Chemistry Xi'an Jiaotong University  Xi'an 710049 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjing","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy Health Science Center Xi'an Jiaotong University  Xi'an 710061 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianglong","family":"Duan","sequence":"additional","affiliation":[{"name":"Second Department of General Surgery Shaanxi Provincial People's Hospital and Third Affiliated Hospital of Xi'an Jiaotong University  Xi'an 710068 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Chen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences  Changchun 130022 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhishen","family":"Ge","sequence":"additional","affiliation":[{"name":"Engineering Research Center of Energy Storage Materials 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