{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T12:06:25Z","timestamp":1789733185301,"version":"4.0.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,11,23]],"date-time":"2023-11-23T00:00:00Z","timestamp":1700697600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52002074"],"award-info":[{"award-number":["52002074"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019180","name":"HORIZON EUROPE European Research Council","doi-asserted-by":"publisher","award":["804519"],"award-info":[{"award-number":["804519"]}],"id":[{"id":"10.13039\/100019180","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Halide perovskites are crystalline semiconductors with exceptional optoelectronic properties, rapidly developing toward large\u2010scale applications. Lead (II) (Pb\n                    <jats:sup>2+<\/jats:sup>\n                    ) is the core element used to prepare halide perovskites. Pb\n                    <jats:sup>2+<\/jats:sup>\n                    can displace key 2+ elements, including calcium, zinc and iron, that regulate vital physiological functions. Sn\n                    <jats:sup>2+<\/jats:sup>\n                    can replace Pb\n                    <jats:sup>2+<\/jats:sup>\n                    within the perovskite structure and, if accidentally dispersed in the environment, it readily oxidizes to Sn\n                    <jats:sup>4+<\/jats:sup>\n                    , which is compatible with physiological functions and thus potentially safe. The 3+ salt bismuth (III) (Bi\n                    <jats:sup>3+<\/jats:sup>\n                    ) is also potentially safe for the same reason and useful to prepare double perovskites. Here, this work studies the biotoxicity of Pb, Sn, and Bi perovskites in mice for the first time. This work analyses histopathology and growth of mice directly exposed to perovskites and investigate the development of their offspring generation. This study provides the screening of organs and key physiological functions targeted by perovskite exposure to design specific studies in mammalians.\n                  <\/jats:p>","DOI":"10.1002\/adma.202306860","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T16:28:01Z","timestamp":1694622481000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Biotoxicity of Halide Perovskites in Mice"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8730-0713","authenticated-orcid":false,"given":"Guixiang","family":"Li","sequence":"first","affiliation":[{"name":"Key Lab for Special Functional Materials Ministry of Education National &amp; Local Joint Engineering Research Center for High\u2010efficiency Display and Lighting Technology School of Materials Science and Engineering and Collaborative Innovation Center of Nano Functional Materials and Applications Henan University  Kaifeng 475004 China"},{"name":"Helmholtz\u2010Zentrum Berlin f\u00fcr Materialien und Energie  Kekul\u00e9stra\u00dfe 5 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong\u2010Tao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Life Science and Technology Xinxiang Medical University Xinxiang 453002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0189-8038","authenticated-orcid":false,"given":"Feng","family":"Yang","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Photovoltaic Materials School of Physics Henan Normal University  Xinxiang 453007 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0360-7791","authenticated-orcid":false,"given":"Meng","family":"Li","sequence":"additional","affiliation":[{"name":"Key Lab for Special Functional Materials Ministry of Education National &amp; Local Joint Engineering Research Center for High\u2010efficiency Display and Lighting Technology School of Materials Science and Engineering and Collaborative Innovation Center of Nano Functional Materials and Applications Henan University  Kaifeng 475004 China"},{"name":"Helmholtz\u2010Zentrum Berlin f\u00fcr Materialien und Energie  Kekul\u00e9stra\u00dfe 5 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Lab for Special Functional Materials Ministry of Education National &amp; Local Joint Engineering Research Center for High\u2010efficiency Display and Lighting Technology School of Materials Science and Engineering and Collaborative Innovation Center of Nano Functional Materials and Applications Henan University  Kaifeng 475004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6486-0737","authenticated-orcid":false,"given":"Jorge","family":"Pascual","sequence":"additional","affiliation":[{"name":"Helmholtz\u2010Zentrum Berlin f\u00fcr Materialien und Energie  Kekul\u00e9stra\u00dfe 5 12489 Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1707-499X","authenticated-orcid":false,"given":"Zhao\u2010Kui","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano &amp; Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon\u2010Based Functional Materials &amp; Devices Joint International Research Laboratory of Carbon\u2010Based Functional Materials and Devices Soochow University  Suzhou 215123 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi\u2010Zhe","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Life Science and Technology Xinxiang Medical University Xinxiang 453002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin\u2010Yuan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Life Science and Technology Xinxiang Medical University Xinxiang 453002 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai\u2010Rui","family":"Liu","sequence":"additional","affiliation":[{"name":"Henan Key Laboratory of Photovoltaic Materials School of Physics Henan Normal University  Xinxiang 453007 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Bo","family":"Zhao","sequence":"additional","affiliation":[{"name":"Key Lab for Special Functional Materials Ministry of Education National &amp; Local Joint Engineering Research Center for High\u2010efficiency Display and Lighting Technology School of Materials Science and Engineering and Collaborative Innovation Center of Nano Functional Materials and Applications Henan University  Kaifeng 475004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh\u2010Ting","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering National Chung Hsing University  145 Xingda Rd. 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