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Herein, living\n                    <jats:italic>Chlorella<\/jats:italic>\n                    \u2010loaded poly(ionic liquid)\u2010based microneedles (PILMN\u2010Chl) are constructed for microacupuncture oxygen and antibacterial therapy against methicillin\u2010resistant\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    (MRSA)\u2010infected chronic diabetic wounds. The PILMN\u2010Chl can stably and continuously produce oxygen for more than 30\u00a0h due to the photosynthesis of the loaded self\u2010supported\n                    <jats:italic>Chlorella<\/jats:italic>\n                    . By combining the barrier penetration capabilities of microneedles, the continuous and sufficient oxygen supply of\n                    <jats:italic>Chlorella<\/jats:italic>\n                    , and the sterilization activities of PIL, the PILMN\u2010Chl can accelerate chronic diabetic wounds in vivo by topical targeted sterilization and hypoxia relief in deep parts of wounds. Thus, the self\u2010oxygen produced microneedles modality may provide a promising and facile therapeutic strategy for treating chronic, hypoxic, and infected diabetic wounds.\n                  <\/jats:p>","DOI":"10.1002\/adma.202307585","type":"journal-article","created":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T18:13:00Z","timestamp":1706897580000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":131,"title":["Chlorella\u2010Loaded Antibacterial Microneedles for Microacupuncture Oxygen Therapy of Diabetic Bacterial Infected Wounds"],"prefix":"10.1002","volume":"36","author":[{"given":"Shuna","family":"Gao","sequence":"first","affiliation":[{"name":"Jiangsu Engineering Laboratory of Novel Functional Polymeric Materials Jiangsu Key Laboratory of Advanced Negative Carbon Technologies Suzhou Key Laboratory of Soft Material and New Energy College of Chemistry Chemical Engineering and Materials Science Soochow University  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