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In this context, antimicrobial coatings emerge as a promising prophylactic strategy to reduce the transmission of pathogens and control infections. Here, antimicrobial door handle covers to prevent cross\u2010contamination are prepared by incorporating iodine\u2010loaded UiO\u201066 microparticles into a potentially biodegradable polyurethane polymer (Baycusan eco E 1000). These covers incorporate MOF particles that serve as both storage reservoirs and delivery systems for the biocidal iodine. Under realistic touching conditions, the door handle covers completely inhibit the transmission of Gram\u2010positive bacterial species (\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    , and\n                    <jats:italic>Enterococcus faecalis<\/jats:italic>\n                    ), Gram\u2010negative bacterial species (\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    ,\n                    <jats:italic>Pseudomonas aeruginosa<\/jats:italic>\n                    , and\n                    <jats:italic>Acinetobacter baumannii<\/jats:italic>\n                    ), and fungi (\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    ). The covers remain effective even after undergoing multiple contamination cycles, after being cleaned, and when tinted to improve discretion and usability. Furthermore, as the release of iodine from the door handle covers follow hindered Fickian diffusion, their antimicrobial lifetime is calculated to be as long as approximately two years. Together, these results demonstrate the potential of these antimicrobial door handle covers to prevent cross\u2010contamination, and underline the efficacy of integrating MOFs into innovative technologies.\n                  <\/jats:p>","DOI":"10.1002\/adma.202403813","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T11:49:32Z","timestamp":1716292172000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Metal\u2013Organic Framework\u2010Based Antimicrobial Touch Surfaces to Prevent Cross\u2010Contamination"],"prefix":"10.1002","volume":"37","author":[{"given":"Javier","family":"Fonseca","sequence":"first","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and The Barcelona Institute of Science and Technology  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Departament de Qu\u00edmica Facultat de Ci\u00e8ncies Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Cano\u2010Sarabia","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and The Barcelona Institute of Science and Technology  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Departament de Qu\u00edmica Facultat de Ci\u00e8ncies Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Cort\u00e9s","sequence":"additional","affiliation":[{"name":"Departament de Gen\u00e8tica i Microbiologia Facultat de Ci\u00e8ncies Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Saldo","sequence":"additional","affiliation":[{"name":"Centre d'Innovaci\u00f3 Recerca i Transfer\u00e8ncia en Tecnologia dels Aliments (CIRTTA) Departament de Ci\u00e8ncia Animal i dels Aliments Facultat de Veterin\u00e0ria Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Montpey\u00f3","sequence":"additional","affiliation":[{"name":"Institut de Biotecnologia i Biomedicina Departament de Bioqu\u00edmica i de Biologia Molecular Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"Institut de Biotecnologia i Biomedicina Departament de Bioqu\u00edmica i de Biologia Molecular Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red Bioingenier\u00eda Biomateriales y Nanomedicina (CIBER\u2010BBN)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Llagostera","sequence":"additional","affiliation":[{"name":"Departament de Gen\u00e8tica i Microbiologia Facultat de Ci\u00e8ncies Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inhar","family":"Imaz","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and The Barcelona Institute of Science and Technology  Campus UAB, Bellaterra Barcelona 08193 Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1325-9161","authenticated-orcid":false,"given":"Daniel","family":"Maspoch","sequence":"additional","affiliation":[{"name":"Catalan Institute of Nanoscience and Nanotechnology (ICN2) CSIC and The Barcelona Institute of Science and Technology  Campus UAB, Bellaterra Barcelona 08193 Spain"},{"name":"Departament de Qu\u00edmica Facultat de Ci\u00e8ncies Universitat Aut\u00f2noma de Barcelona (UAB)  Cerdanyola del Vall\u00e8s Barcelona 08193 Spain"},{"name":"ICREA  Pg. 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