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However, the pulse wave varies drastically among individuals or even over time in the same individual, presenting significant challenges for the existing pulse sensing systems. Inspired by pulse diagnosis methods in traditional Chinese medicine (TCM), this work reports a self\u2010adaptive pressure sensing platform (PSP) that combines the fully printed flexible pressure sensor array with an adaptive wristband\u2010style pressure system can identify the optimal pulse signal. Besides the detected pulse rate\/width\/length, \u201cCun, Guan, Chi\u201d position, and \u201cfloating, moderate, sinking\u201d pulse features, the PSP combined with a machine learning\u2010based linear regression model can also accurately predict blood pressure such as systolic, diastolic, and mean arterial pressure values. The developed diagnostic platform is demonstrated for highly reliable long\u2010term monitoring and analysis of pulse and blood pressure across multiple human subjects over time. The design concept and proof\u2010of\u2010the\u2010concept demonstrations also pave the way for the future developments of flexible sensing devices\/systems for adaptive individualized monitoring in the complex practical environments for personalized medicine, along with the support for the development of digital TCM.<\/jats:p>","DOI":"10.1002\/adma.202410312","type":"journal-article","created":{"date-parts":[[2024,9,30]],"date-time":"2024-09-30T05:15:37Z","timestamp":1727673337000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":108,"title":["Traditional Chinese Medicine (TCM)\u2010Inspired Fully Printed Soft Pressure Sensor Array with Self\u2010Adaptive Pressurization for Highly Reliable Individualized Long\u2010Term Pulse Diagnostics"],"prefix":"10.1002","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7464-3565","authenticated-orcid":false,"given":"Xin","family":"Wang","sequence":"first","affiliation":[{"name":"Pen\u2010Tung Sah Institute of Micro\u2010Nano Science and Technology Xiamen University  Xiamen 361102 China"},{"name":"Shenzhen Research Institute of Xiamen University Xiamen University  Shenzhen 518000 China"},{"name":"School of Automation and Software Engineering Shanxi University  Taiyuan 030006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guirong","family":"Wu","sequence":"additional","affiliation":[{"name":"Pen\u2010Tung Sah Institute of Micro\u2010Nano Science and Technology Xiamen University  Xiamen 361102 China"},{"name":"Shenzhen Research Institute of Xiamen University Xiamen University  Shenzhen 518000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xikuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Instrumentation Science and Dynamic Measurement Ministry of Education North University of China  Taiyuan 030051 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Lv","sequence":"additional","affiliation":[{"name":"School of Automation and Software Engineering Shanxi University  Taiyuan 030006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zekun","family":"Yang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Instrumentation Science and Dynamic Measurement Ministry of Education North University of China  Taiyuan 030051 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueli","family":"Nan","sequence":"additional","affiliation":[{"name":"School of Automation and Software Engineering Shanxi University  Taiyuan 030006 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zengxing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Pen\u2010Tung Sah Institute of Micro\u2010Nano Science and Technology Xiamen University  Xiamen 361102 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyang","family":"Xue","sequence":"additional","affiliation":[{"name":"Pen\u2010Tung Sah Institute of Micro\u2010Nano Science and Technology Xiamen University  Xiamen 361102 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanyu","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Engineering Science and Mechanics The Pennsylvania State University  University Park PA 16802 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5964-2337","authenticated-orcid":false,"given":"Libo","family":"Gao","sequence":"additional","affiliation":[{"name":"Pen\u2010Tung Sah Institute of Micro\u2010Nano Science and Technology Xiamen University  Xiamen 361102 China"},{"name":"Shenzhen Research Institute of Xiamen University Xiamen University  Shenzhen 518000 China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,30]]},"reference":[{"key":"e_1_2_8_1_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001052"},{"key":"e_1_2_8_2_1","first-page":"548","volume":"42","author":"Pelliccia A.","year":"2020","journal-title":"Eur. 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