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Here, magnetically\u2010guided liquid metal microrobots composed of gallium\u2010indium alloys embedded with Fe nanoparticles are introduced. The unique combination of magnetic maneuverability, high surface tension, intrinsic radiopacity, and deformability allows liquid metal\u2010based microbots to overcome limitations of both hard microrobots and fragile droplet\u2010based systems. Under magnetic actuation, liquid metal\u2010based magnetic microrobots exhibit controllable rolling and upstream locomotion resembling neutrophil\u2010like navigation, enabling precise maneuvering even against physiological flow. Bridging in vitro with in vivo experiments, quail egg chorioallantoic membrane models are used to demonstrate guided transport of these microrobots through blood vessels, accumulation at tumor xenografts, and migration within subcutaneous tissues. Moreover, their strong X\u2010ray visibility enables real\u2010time fluoroscopic tracking, validated in porcine heart vasculature. Importantly, liquid metal\u2010based magnetic microbots can cross endothelial barriers in a vascular flow\u2010on\u2010a\u2010chip platform, while maintaining endothelial biocompatibility. By integrating deformability, magnetic steerability, and imaging visibility, liquid metal\u2010based microrobots establish a powerful platform for minimally invasive transvascular navigation. This work highlights the potential of liquid metal\u2010based magnetic microrobots for targeted drug delivery, image\u2010guided therapy, and intelligent biomedical interventions.<\/jats:p>","DOI":"10.1002\/adma.202518382","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T06:48:56Z","timestamp":1766213336000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4468-6003","authenticated-orcid":false,"given":"Xiaohui","family":"Ju","sequence":"first","affiliation":[{"name":"Future Energy and Innovation Laboratory Central European Institute of Technology Brno University of Technology  Purky\u0148ova 123 Brno 61200 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4356-2363","authenticated-orcid":false,"given":"Roshan","family":"Velluvakandy","sequence":"additional","affiliation":[{"name":"Future Energy and Innovation Laboratory Central European Institute of Technology Brno University of Technology  Purky\u0148ova 123 Brno 61200 Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-9308-1883","authenticated-orcid":false,"given":"Xianghua","family":"Wu","sequence":"additional","affiliation":[{"name":"Future Energy and Innovation Laboratory Central European Institute of Technology Brno University of Technology  Purky\u0148ova 123 Brno 61200 Czech Republic"},{"name":"State Key Laboratory of Advanced Technology for Materials Synthesis and Processing International School of Materials Science and Engineering Wuhan University of Technology  122 Luoshi Road Wuhan 430070 P.R. 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