{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T04:02:09Z","timestamp":1792123329316,"version":"4.4.0"},"reference-count":64,"publisher":"Wiley","issue":"44","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The design of hydrogel\u2010based artificial tissues capable of reversible, programmed, and complex motions requires both stimuli\u2010responsiveness and structural anisotropy. In this work, non\u2010unidirectional anisotropies are generated in biocompatible hydrogels by structuring magnetic particle suspensions into lamellar architectures through two distinct routes: the application of an unsteady magnetic field to a quiescent sample, and the superposition of a steady magnetic field with shear flow. In both approaches, magnetic particles undergo directed self\u2010assembly within a polymer matrix that subsequently gels, thereby preserving the formed structures. We analyze the assembly kinetics, characterize the resulting lamellar patterns, and construct phase diagrams for each method. The morphology and periodicity of the lamellae are shown to depend strongly on geometric confinement, enabling tunable interlamellar spacing from tens to hundreds of microns. Crucially, it is demonstrated that the resulting layered hydrogels can confine human fibroblasts between adjacent particle\u2010rich lamellae, maintain cell viability above 95% over 7 days of culture, and promote preferential cell alignment parallel to the layered structures. These findings establish magnetic field\u2010directed lamellar structuring as a versatile route to anisotropic hydrogels with programmable internal architecture, opening new opportunities in tissue engineering, bioactuation, and soft robotics.<\/jats:p>","DOI":"10.1002\/adma.73847","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:54:48Z","timestamp":1782971688000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Engineering Layered Magnetic Hydrogels for Cell Placement via Shear and Magnetic Field\u2010Induced Assembly"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9341-3052","authenticated-orcid":false,"given":"Guillermo","family":"Camacho","sequence":"first","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4909-9721","authenticated-orcid":false,"given":"Jose R.","family":"Morillas","sequence":"additional","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-8703-7875","authenticated-orcid":false,"given":"Jes\u00fas","family":"Garc\u00eda\u2010Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8033-8073","authenticated-orcid":false,"given":"Stefania","family":"Nardecchia","sequence":"additional","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7704-881X","authenticated-orcid":false,"given":"\u00d3scar","family":"Mart\u00ednez\u2010Cano","sequence":"additional","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-2272","authenticated-orcid":false,"given":"Juan","family":"de Vicente","sequence":"additional","affiliation":[{"name":"F2N2Lab, Magnetic Soft Matter Group, Department of Applied Physics, Faculty of Sciences University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,1]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/1941014a0"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201703045"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.07.014"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738109350438"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3BM00744H"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mser.2017.07.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201708196"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/aisy.201900135"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2778"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201801934"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201503950"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2022.1040492"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cocis.2025.101903"},{"key":"e_1_2_8_15_1","unstructured":"S.Nardecchia J.Garc\u00eda\u2010Guti\u00e9rrez G.Camacho J. 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