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However, their exploitation remains limited by the inherently large absorption blueshift (usually &gt;100\u00a0nm) arising from strong H\u2010type excitonic coupling in conventional parallel\u2010packed H\u2010aggregates, forcing short\u2010wavelength laser excitation with poor tissue penetration. Herein, this study reports a planarity\u2010hindrance co\u2010balance strategy to develop donor\u2010\u03c0\u2010acceptor\u2010based antiparallel\u2010packed H\u2010aggregates with minimal absorption blueshift for type I PDT. The results demonstrate that \u03c0\u2010bridge planarization drives H\u2010packing, while donor\u2010site steric tuning dictates the blueshift by modulating slipping angles and \u03c0\u2010\u03c0 overlapping degree, and a steric threshold (Me\/OMe) is identified beyond which blueshift becomes invariant. The optimized MTBSIC molecules form H\u2010aggregates with an exceptionally small blueshift of 15\u00a0nm over its monomers. MTBSIC H\u2010aggregates further display markedly enhanced type I ROS generation and improved photothermal conversion ability over their amorphous counterparts possessing similar monomeric photophysical properties. Mechanistic analyses reveal that H\u2010packing promotes both intersystem crossing and intermolecular charge transfer\/separation, synergistically boosting type I ROS production. MTBSIC H\u2010aggregates further achieve potent tumor inhibition with high biocompatibility both in vitro and in vivo. This work establishes a generalizable molecular design paradigm for near\u2010monomer\u2010like H\u2010aggregates for high\u2010performance phototheranostics.<\/jats:p>","DOI":"10.1002\/adma.73868","type":"journal-article","created":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T15:52:44Z","timestamp":1782921164000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["A Planarity\u2010Hindrance Co\u2010Balance Strategy to Develop Antiparallel H\u2010Aggregates With Minimal Absorbance Blueshift for Type I Photodynamic Therapy"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1357-1598","authenticated-orcid":false,"given":"Yubo","family":"Liu","sequence":"first","affiliation":[{"name":"State Key Laboratory of Luminescent Materials and Devices Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates School of Materials Science and Engineering AIE Institute South 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