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Here, we present a self\u2010growing conductive volumetric interface (SCOVE) that transforms surface\u2010confined biointerfaces into tissue\u2010integrated, three\u2010dimensional conductive networks. SCOVE is delivered as an injectable hydrogel precursor containing the tissue\u2010permeable conductive monomer 3,4\u2010ethylenedioxythiophene\u2010acetic acid sodium salt (ETE), which rapidly infiltrates infarcted myocardium and undergoes endogenous glucose\u2010triggered oxidative polymerization to self\u2010grow a conductive polyETE network in situ. The resulting hydrogel gels within 1\u00a0min, reaches cardiac\u2010mimetic conductivity (\u223c1 S m\n                    <jats:sup>\u2212<\/jats:sup>\n                    <jats:sup>1<\/jats:sup>\n                    ) within 45\u00a0min, and preserves native myocardial mechanics without inducing tissue stiffening. In a rat myocardial infarction model, SCOVE penetrates the infarct, reduces scar resistivity by 2.54\u2010fold compared with conventional 2D conductive patches, restores electrical coupling among residual cardiomyocytes, enhances Cx43 expression, and accelerates impulse propagation. By replacing static, surface\u2010confined conductive patches with self\u2010growing volumetric biointerfaces, this work establishes a generalizable strategy for reconstructing tissue electrophysiology and advancing bioelectronic therapies for myocardial infarction and other electrically dysfunctional tissues.\n                  <\/jats:p>","DOI":"10.1002\/adma.74527","type":"journal-article","created":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T08:13:37Z","timestamp":1786349617000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Self\u2010Growing Conductive Hydrogels Establish Volumetric Biointerfaces for Cardiac Conduction Restoration"],"prefix":"10.1002","volume":"38","author":[{"given":"Fucheng","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Mechanical and Energy Engineering Southern University of Science and Technology  Shenzhen 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