{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:45:05Z","timestamp":1792680305050,"version":"4.5.0"},"reference-count":67,"publisher":"Wiley","issue":"59","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFA1205200"],"award-info":[{"award-number":["2022YFA1205200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U22A20249"],"award-info":[{"award-number":["U22A20249"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011213","name":"State Key Laboratory of Molecular Engineering of Polymers","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011213","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Zwitterionic hydrogels possess exceptional antifouling characteristics and biocompatibility, but their weak mechanical strength limits implantable applications. Existing enhancement strategies either introduce non\u2010zwitterionic phases that compromise antifouling performance or employ zwitterionic fillers that still fall short of achieving high mechanical robustness. Here, we present a kinetic\u2010locking strategy to fabricate strong, antifouling zwitterionic composite fibers for hydrogel reinforcement. Co\u2010dissolving hydrophilic zwitterionic and hydrophobic polymers followed by electrospinning kinetically traps molecular entanglement via ultrafast solvent evaporation, suppressing thermodynamic phase separation. The kinetically preserved molecular entanglement maintains the antifouling properties of the zwitterionic component while enabling the hydrophobic polymer to contribute substantial mechanical strength. In addition, the entanglement and electrostatic interaction between the fibers and the zwitterionic matrix form a robust interface for efficient load transfer. This approach is broadly applicable across polymer systems, producing hydrogels that integrate high tensile strength (2.48\u00a0MPa), extreme stretchability (1040%), and remarkable fracture toughness (27.76\u00a0kJ m\n                    <jats:sup>\u22122<\/jats:sup>\n                    \u2014a three\u2010order\u2010of\u2010magnitude improvement over pure zwitterionic hydrogels) without sacrificing antifouling properties. These advances support reliable long\u2010term in vivo electromyography recording and effective sciatic nerve stimulation. The work establishes kinetic locking as a general design paradigm to overcome the strength\u2013antifouling trade\u2010off in zwitterionic hydrogels, advancing durable, long\u2010term implantable bioelectronics.\n                  <\/jats:p>","DOI":"10.1002\/adma.74810","type":"journal-article","created":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T07:53:11Z","timestamp":1787644391000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Kinetic\u2010Locked Fiber Networks Enable Anti\u2010Fouling, Mechanically Robust Zwitterionic Hydrogels"],"prefix":"10.1002","volume":"38","author":[{"given":"Xiaoru","family":"Dong","sequence":"first","affiliation":[{"name":"College of Smart Materials and Future Energy State Key Laboratory of Molecular Engineering of Polymers Fudan University  Shanghai 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