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Clinical practice has long pursued continuous and on\u2010demand ICP monitoring across the risk window for accurate ACS management. Existing probe manometry imposes pain and infection risk, particularly during prolonged wired indwelling or repeated punctures. Implantable electronic sensors enable wireless monitoring, but face biocompatibility and stability challenges from the mismatched human\u2010machine interface. Here, we present an injectable, bioadhesive ultrasonic sensor (metagel sensor) that enables continuous and wireless on\u2010demand monitoring of intracompartmental pressure across the post\u2010njury clinical window. The ultrasonic modulation properties of the metastructural hydrogel encode pressure signals into reflected ultrasonic waves as measurable bandgap shifts, enabling fully passive wireless readout. The metagel exhibited substantial biodegradation over 14 weeks in rats. In a porcine model, we demonstrated the capability of the metagel sensor in continuous acute\u2010phase ICP monitoring and repeated wireless on\u2010demand interrogation over 10 days. Simultaneously decoupled signals related to respiration and pulse offer additional physiological information relevant to ACS assessment.<\/jats:p>","DOI":"10.1002\/adma.75097","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T06:22:59Z","timestamp":1789971779000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Injectable Bioadhesive Ultrasonic Sensor for Continuous and Wireless On\u2010Demand Pressure Monitoring in Acute Compartment Syndrome"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-1050-0916","authenticated-orcid":false,"given":"Lejie","family":"Qin","sequence":"first","affiliation":[{"name":"School of Integrated Circuits and Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology  Wuhan 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