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Distinct from conventional food sensors, emerging food\u2010interfaced bioelectronic platforms combine advances in materials science, molecular recognition, and device engineering to enable direct and in situ access to food\u2010relevant information. Recent efforts have increasingly focused on sustainable, biocompatible, and, in some cases, edible materials that can safely interface with foods while maintaining robust performance in chemically and mechanically heterogeneous environments. Coupled with unobtrusive, multimodal sensing platforms and data\u2010driven analytical frameworks, these systems offer new opportunities for real\u2010time food profiling, informed consumption, and waste reduction. This review surveys recent progress in food\u2010interfaced sensing technologies, with particular emphasis on materials innovations, interface design considerations, sensing and signal transduction strategies, and application\u2010driven data interpretation. We further discuss the key translational challenges associated with validation, scalability, and regulatory adoption. By bridging materials, devices, and food systems, food\u2010interfaced bioelectronics have the potential to transform food monitoring, food safety, and personalized nutrition.<\/jats:p>","DOI":"10.1002\/adma.75196","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:46:45Z","timestamp":1790837205000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Food\u2010Interfaced Bioelectronics for In Situ Molecular Food Profiling"],"prefix":"10.1002","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6320-034X","authenticated-orcid":false,"given":"Jeonghee","family":"Yeom","sequence":"first","affiliation":[{"name":"Andrew and Peggy Cherng Department of Medical Engineering Division of Engineering and Applied Science California Institute of Technology  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5088-3441","authenticated-orcid":false,"given":"Shadman","family":"Khan","sequence":"additional","affiliation":[{"name":"Andrew and Peggy Cherng Department of Medical Engineering Division of Engineering and Applied Science California Institute of Technology  Pasadena California USA"},{"name":"School of Environmental Sciences University of Guelph  Guelph ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8503-4562","authenticated-orcid":false,"given":"Wei","family":"Gao","sequence":"additional","affiliation":[{"name":"Andrew and Peggy Cherng Department of Medical Engineering Division of Engineering and Applied Science California Institute of Technology  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aei.2011.07.007"},{"key":"e_1_2_10_3_1","unstructured":"United Nations Environment Programme \u201cFood Waste Index Report 2024 \u201d Food Waste Index Report 2024 2024."},{"key":"e_1_2_10_4_1","unstructured":"U.S. Department of Agriculture \u201cWhy Should We Care about Food Waste? \u201d Why Should We Care about Food Waste? 2025 https:\/\/www.usda.gov\/about\u2010food\/food\u2010safety\/food\u2010loss\u2010and\u2010waste\/why\u2010should\u2010we\u2010care\u2010about\u2010food\u2010waste accessed December 19 2025."},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2016.02.026"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.2c00823"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587\u2010019\u20100045\u2010y"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587\u2010019\u20100040\u20103"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adx6491"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41928\u2010025\u201001407\u20100"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201806739"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/admt.202001242"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202300875"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/chemosensors13050161"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/admt.201800488"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/admt.202000757"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.17.1.237"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jada.2004.01.010"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.12.017"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05401"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00221\u2010005\u20102376\u20109"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/39807"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bju014"},{"key":"e_1_2_10_24_1","volume-title":"Dietary Reference Intakes: The Essential Guide to Nutrient Requirements","author":"Meyers L. 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