{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:58:45Z","timestamp":1790823525098,"version":"4.1.0"},"reference-count":55,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22475243"],"award-info":[{"award-number":["22475243"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["61801525"],"award-info":[{"award-number":["61801525"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFA1207804"],"award-info":[{"award-number":["2024YFA1207804"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A1515011685"],"award-info":[{"award-number":["2024A1515011685"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011302","name":"State Key Laboratory of Advanced Technology for Materials Synthesis and Processing","doi-asserted-by":"publisher","award":["2025\u2010KF\u201010"],"award-info":[{"award-number":["2025\u2010KF\u201010"]}],"id":[{"id":"10.13039\/501100011302","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Pressure sensors, with their immense potential for detecting fine physiological activities and monitoring neurological disease\u2010related signals, face significant challenges, including the occurrence of signal artifacts during stretching and low comfort due to poor breathability. Here, a bioinspired interlocking hierarchical heterostructure (BIHH) is synergistically designed by anchoring a porous textile\u2010microstructured ionogel to stretchable laser\u2010induced graphene electrodes to simultaneously enhance strain insensitivity, pressure sensing performance, and wearable comfort. This modulus\u2010gradient heterogeneous mechanical network induces interfacial strain partitioning: tensile strain dissipates along porous Ecoflex frameworks, while the pressure\u2010sensitive domains are mechanically locked against deformation. Consequently, the sensor exhibits a mere 2% signal variation under 100% strain, maintaining consistent sensing capability even under severe stretching. Meanwhile, the hierarchical porous microstructure reconciles high\u2010performance iontronic pressure sensing with skin\u2010conformable breathability for array\u2010based touch and human physiological signal perception. Furthermore, by integrating artificial intelligence recognition algorithms, a five\u2010channel finger tapping assessment system achieves an accuracy of 97% in distinguishing different tapping patterns for the early auxiliary screening and rehabilitation of neurodegenerative diseases. This effective strategy opens a promising path for designing devices that reduce motion artifact interference while enhancing pressure sensing performance and comfort for on\u2010skin physiological activity monitoring.<\/jats:p>","DOI":"10.1002\/adma.75211","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:32:44Z","timestamp":1790821964000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Bioinspired Interlocking Hierarchical Heterostructures Endow Iontronic Pressure Sensors With Superior Strain Insensitivity, Air Permeability, and Sensing Performance for Neurodegenerative Disease Assessment"],"prefix":"10.1002","author":[{"given":"Dijie","family":"Yao","sequence":"first","affiliation":[{"name":"State Key Laboratory of Optoelectronic Materials and Technologies and the Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9560-4383","authenticated-orcid":false,"given":"Qiuhua","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine The First Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Neurology The First Affiliated Hospital Sun Yat\u2010Sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huizhi","family":"Chen","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Advanced Drug Delivery and Biosensing Research and Development School of Pharmacy and Dongguan Innovation Institute Guangdong Medical University  Dongguan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3226-9624","authenticated-orcid":false,"given":"Cheng","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery West China Hospital Sichuan University  Chengdu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajia","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine The First Affiliated Hospital Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4165-5498","authenticated-orcid":false,"given":"Zhenwen","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Rehabilitation Medicine Guangzhou Red Cross Hospital of Jinan University  Guangzhou Guangdong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1848-8561","authenticated-orcid":false,"given":"Kai","family":"Tao","sequence":"additional","affiliation":[{"name":"School of Mechanical Engineering Ministry of Education Key Laboratory of Micro and Nano Systems For Aerospace Northwestern Polytechnical University  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4234-1359","authenticated-orcid":false,"given":"Gang","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7603-9436","authenticated-orcid":false,"given":"Fei","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Optoelectronic Materials and Technologies and the Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5318-4267","authenticated-orcid":false,"given":"Fengwei","family":"Huo","sequence":"additional","affiliation":[{"name":"The Institute of Flexible Electronics (IFE, Future Technologies) Xiamen University  Xiamen Fujian China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0849-1492","authenticated-orcid":false,"given":"Junyou","family":"Yang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Materials Processing and Die &amp; Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3065-6858","authenticated-orcid":false,"given":"Jin","family":"Wu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Optoelectronic Materials and Technologies and the Guangdong Province Key Laboratory of Display Material and Technology School of Electronics and Information Technology Sun Yat\u2010sen University  Guangzhou China"},{"name":"State Key Laboratory of Materials Processing and Die &amp; Mould Technology School of Materials Science and Engineering Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1255555"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010025\u201003834\u20100"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468\u20102667(21)00249\u20108"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adv2124"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201055649\u20101"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202500076"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202309868"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010019\u201014054\u20109"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202003464"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202413141"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abi4563"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202414425"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202502583"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202313824"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.74742"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c02359"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2019.08.013"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202107281"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202316339"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010017\u201002685\u20109"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202309629"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.163763"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2024.110482"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202502196"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2023.108170"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010023\u201038274\u20102"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41528\u2010025\u201000420\u20109"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c05570"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202416482"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nanoen.2023.108367"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6714"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202205158"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202305777"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202201663"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202303949"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0305\u20104179(77)90004\u20103"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2005.04.012"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201050797\u2010w"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.153525"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2024.05.001"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202304409"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202401532"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.1c00640"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202312034"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c04939"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201703004"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.20517\/ss.2023.24"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2024.04.009"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201801114"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2023.02.047"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD\u2010221297"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2023.3296883"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cortex.2020.08.001"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.3233\/ADR\u2010210065"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy155"}],"container-title":["Advanced Materials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adma.75211","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/adma.75211","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/adma.75211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:32:46Z","timestamp":1790821966000},"score":1,"resource":{"primary":{"URL":"https:\/\/advanced.onlinelibrary.wiley.com\/doi\/10.1002\/adma.75211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,30]]},"references-count":55,"alternative-id":["10.1002\/adma.75211"],"URL":"https:\/\/doi.org\/10.1002\/adma.75211","archive":["Portico"],"relation":{},"ISSN":["0935-9648","1521-4095"],"issn-type":[{"value":"0935-9648","type":"print"},{"value":"1521-4095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,30]]},"assertion":[{"value":"2026-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e75211"}}