{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:59:05Z","timestamp":1790740745342,"version":"4.1.0"},"reference-count":50,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22125701 to K.L"],"award-info":[{"award-number":["22125701 to K.L"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22404059 to J.S"],"award-info":[{"award-number":["22404059 to J.S"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004106","name":"East China Normal University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004106","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["advanced.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Advanced Materials"],"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Glassy gels are indispensable for applications ranging from structural composites to bioelectronics, yet their design is plagued by an intrinsic paradox where the rigid molecular constraints that endow high stiffness simultaneously restrict polymer chain dynamics, precluding the energy dissipation mechanisms essential for toughness. Here, we circumvent this fundamental trade\u2010off through an in situ molecular constraint\u2010induced ordered glassification strategy. By restricting localized conformations within a confined hydration environment, we drive the spontaneous assembly of long\u2010range ordered, load\u2010bearing nanodomains within a soft gel matrix. These domains function as rigid sacrificial units during initial deformation. Critically, they undergo a progressive, strain\u2010activated dissociation that redistributes local stress and dissipates mechanical energy at the bulk scale. Unlike conventional post\u2010treated gels, our material undergoes a rubbery\u2010to\u2010glassy transition in situ without external intervention, yielding a 3500\u2010fold modulus enhancement and a toughness of 289\u00a0MJ m\n                    <jats:sup>\u22123<\/jats:sup>\n                    , exceeding many reported high\u2010modulus hydrogels and ionic gels. Furthermore, this molecular design imparts multimodal functionality, including strong yet water\u2010removable adhesion (\u223c17\u00a0MPa to glass), superior impact resistance, and water\u2010responsive shape programmability. This ordered glassification paradigm establishes a versatile molecular engineering route to create load\u2010bearing gels that synergistically integrate stiffness, toughness, and adaptive intelligence, redefining the performance envelope of hydrated soft matter.\n                  <\/jats:p>","DOI":"10.1002\/adma.75223","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:24:11Z","timestamp":1790738651000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["In Situ Ordered Glassification of Gels for Exceptional Stiffness and Toughness"],"prefix":"10.1002","author":[{"given":"Xianjia","family":"Lin","sequence":"first","affiliation":[{"name":"School of Chemistry and Molecular Engineering Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development East China Normal University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Chemistry Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education) Tsinghua University  Beijing P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8850-0349","authenticated-orcid":false,"given":"Yang","family":"Tian","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Engineering Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development East China Normal University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0878-5191","authenticated-orcid":false,"given":"Kai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Chemistry Engineering Research Center of Advanced Rare Earth Materials (Ministry of Education) Tsinghua University  Beijing P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0114-2206","authenticated-orcid":false,"given":"Jing","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Chemistry and Molecular Engineering Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development East China Normal University  Shanghai P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010023\u201006782\u20102"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010024\u201007564\u20100"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010025\u201009269\u20104"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010023\u201006117\u20101"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586\u2010021\u201003212\u2010z"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg2689"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adn6925"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abg6320"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau9533"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40242\u2010024\u20104195\u20101"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.73010"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565\u2010023\u201001431\u20101"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202411700"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adr9834"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202411372"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202100064"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202508034"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.75646"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202207587"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adv5292"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2417978122"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202523692"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202521809"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202407397"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563\u2010022\u201001195\u20104"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010026\u201070223\u20107"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aec7718"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adh3632"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563\u2010023\u201001697\u20109"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563\u2010026\u201002624\u20104"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adf7075"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.73545"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abb5367"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ade6973"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010024\u201055677\u2010x"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adv7786"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2026.102666"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202307290"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2025.102317"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adv2169"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaz6694"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.73565"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202506748"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.add8527"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010026\u201073850\u20102"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010025\u201066537\u20107"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202400084"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.2977415"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adr7175"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41893\u2010026\u201001776\u20100"}],"container-title":["Advanced 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